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Protein

40S ribosomal protein S6

Gene

rps6

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal proteinUniRule annotation

Enzyme and pathway databases

ReactomeiR-DRE-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DRE-166208 mTORC1-mediated signalling
R-DRE-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DRE-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-DRE-72649 Translation initiation complex formation
R-DRE-72689 Formation of a pool of free 40S subunits
R-DRE-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-DRE-72702 Ribosomal scanning and start codon recognition
R-DRE-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DRE-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DRE-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S6UniRule annotation
Gene namesi
Name:rps6Imported
ORF Names:zgc:92237Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi

Organism-specific databases

ZFINiZDB-GENE-040801-8 rps6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000019778

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000011148

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili217 – 237Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eS6 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1646 Eukaryota
COG2125 LUCA
GeneTreeiENSGT00390000009819
HOVERGENiHBG011441
KOiK02991
OMAiKGYIFRI
OrthoDBiEOG091G089B
TreeFamiTF300035

Family and domain databases

InterProiView protein in InterPro
IPR014401 Ribosomal_S6_euk
IPR001377 Ribosomal_S6e
IPR018282 Ribosomal_S6e_CS
PANTHERiPTHR11502 PTHR11502, 1 hit
PfamiView protein in Pfam
PF01092 Ribosomal_S6e, 1 hit
PIRSFiPIRSF002129 Ribosom_S6_euk, 1 hit
SMARTiView protein in SMART
SM01405 Ribosomal_S6e, 1 hit
PROSITEiView protein in PROSITE
PS00578 RIBOSOMAL_S6E, 1 hit

Sequencei

Sequence statusi: Complete.

Q6DHL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNISFPAT GCQKLIEVDD ERKLRIFYEK RMATEVAADS LGDEWKGYVV
60 70 80 90 100
RISGGNDKQG FPMKQGVLTH GRVRLLLSKG HSCYRPRRTG ERKRKSVRGC
110 120 130 140 150
IVDANLSVLN LVIVRKGEKD IPGLTDSTVP RRLGPKRASR IRKLFNLSKE
160 170 180 190 200
DDVRQYVVRR PLTKEGKKPR TKAPKIQRLV TPRVLQHKRR RIALKRQRTL
210 220 230 240
KNKEAAAEYT KLLAKRMKEA KEKRQEQIAK RRRLSSLRAS TSKSESSQK
Length:249
Mass (Da):28,709
Last modified:August 16, 2004 - v1
Checksum:i887A7719CBAA3F31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU929294 Genomic DNA No translation available.
BC075953 mRNA Translation: AAH75953.1
BC154192 mRNA Translation: AAI54193.1
RefSeqiNP_001003728.1, NM_001003728.1
UniGeneiDr.32392

Genome annotation databases

EnsembliENSDART00000023336; ENSDARP00000011148; ENSDARG00000019778
GeneIDi445028
KEGGidre:445028

Similar proteinsi

Entry informationi

Entry nameiQ6DHL6_DANRE
AccessioniPrimary (citable) accession number: Q6DHL6
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: March 28, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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