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Protein

Leucine-rich repeat-containing protein 57

Gene

lrrc57

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine-rich repeat-containing protein 57
Gene namesi
Name:lrrc57
ORF Names:zgc:92240
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 17

Organism-specific databases

ZFINiZDB-GENE-040718-372. lrrc57.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 238238Leucine-rich repeat-containing protein 57PRO_0000227781Add
BLAST

Proteomic databases

PaxDbiQ6DHL5.
PRIDEiQ6DHL5.

Expressioni

Gene expression databases

BgeeiQ6DHL5.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000064514.

Structurei

3D structure databases

ProteinModelPortaliQ6DHL5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati10 – 3627LRR 1Add
BLAST
Repeati37 – 6226LRR 2Add
BLAST
Repeati64 – 8219LRR 3Add
BLAST
Repeati83 – 10624LRR 4Add
BLAST
Repeati108 – 12821LRR 5Add
BLAST
Repeati129 – 15224LRR 6Add
BLAST
Repeati154 – 17320LRR 7Add
BLAST
Repeati174 – 19926LRR 8Add
BLAST

Sequence similaritiesi

Contains 8 LRR (leucine-rich) repeats.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00840000129676.
HOGENOMiHOG000116557.
HOVERGENiHBG054710.
InParanoidiQ6DHL5.
OMAiSAFTPRI.
OrthoDBiEOG7VTDP7.
PhylomeDBiQ6DHL5.
TreeFamiTF326481.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 5 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 7 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6DHL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNSALKAHL ETSQKTGVFQ LTGKGLTEFP EDLQKLTANL RTVDLSNNKI
60 70 80 90 100
EELPAFIGSF QHLKSFTISC NKLTSLPNDI GKLKKLETLI LNGNQLKQLP
110 120 130 140 150
SSIGQLKSLR TLSLSGNQFK EFPSGLGTLR QLDVLDLSKN QIRVVPAEVA
160 170 180 190 200
ELQAIEINLN QNQISSVTQE VSRTPRLKVL RLEENCLELS SIPLSILTDS
210 220 230
QVSLLSVEGN LFEVKKMRDL EGYDKYMERF TATKKKFA
Length:238
Mass (Da):26,519
Last modified:August 16, 2004 - v1
Checksum:i911BAE3F867CFAA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC075955 mRNA. Translation: AAH75955.1.
RefSeqiNP_001002627.1. NM_001002627.1.
UniGeneiDr.84455.

Genome annotation databases

EnsembliENSDART00000064515; ENSDARP00000064514; ENSDARG00000043938.
GeneIDi436900.
KEGGidre:436900.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC075955 mRNA. Translation: AAH75955.1.
RefSeqiNP_001002627.1. NM_001002627.1.
UniGeneiDr.84455.

3D structure databases

ProteinModelPortaliQ6DHL5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000064514.

Proteomic databases

PaxDbiQ6DHL5.
PRIDEiQ6DHL5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000064515; ENSDARP00000064514; ENSDARG00000043938.
GeneIDi436900.
KEGGidre:436900.

Organism-specific databases

CTDi255252.
ZFINiZDB-GENE-040718-372. lrrc57.

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00840000129676.
HOGENOMiHOG000116557.
HOVERGENiHBG054710.
InParanoidiQ6DHL5.
OMAiSAFTPRI.
OrthoDBiEOG7VTDP7.
PhylomeDBiQ6DHL5.
TreeFamiTF326481.

Miscellaneous databases

PROiQ6DHL5.

Gene expression databases

BgeeiQ6DHL5.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 5 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 7 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiLRC57_DANRE
AccessioniPrimary (citable) accession number: Q6DHL5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: August 16, 2004
Last modified: June 8, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.