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Protein

GTP-binding protein 10

Gene

gtpbp10

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in the ribosome maturation process.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi155 – 1628GTPPROSITE-ProRule annotation
Nucleotide bindingi202 – 2065GTPPROSITE-ProRule annotation
Nucleotide bindingi278 – 2814GTPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
GTP-binding protein 10
Gene namesi
Name:gtpbp10
ORF Names:zgc:92334
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 16

Organism-specific databases

ZFINiZDB-GENE-040718-153. gtpbp10.

Subcellular locationi

  • Nucleusnucleolus

  • Note: Found in the dense fibrillar compartment region of the nucleolus.By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 380380GTP-binding protein 10PRO_0000312632Add
BLAST

Proteomic databases

PaxDbiQ6DHF7.
PRIDEiQ6DHF7.

Expressioni

Gene expression databases

BgeeiQ6DHF7.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000058969.

Structurei

3D structure databases

ProteinModelPortaliQ6DHF7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini149 – 344196OBG-type GPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.PROSITE-ProRule annotation
Contains 1 OBG-type G (guanine nucleotide-binding) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1489. Eukaryota.
COG0536. LUCA.
GeneTreeiENSGT00530000063429.
HOGENOMiHOG000019084.
HOVERGENiHBG104309.
InParanoidiQ6DHF7.
OMAiNLWISDT.
OrthoDBiEOG7DJSMM.
PhylomeDBiQ6DHF7.
TreeFamiTF314774.

Family and domain databases

Gene3Di2.70.210.12. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR031167. G_OBG.
IPR014100. GTP-bd_Obg/CgtA.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11702:SF3. PTHR11702:SF3. 1 hit.
PfamiPF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFiPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
PROSITEiPS51710. G_OBG. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6DHF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVWTSRICFR KYGNFVDNVR LYVRGGTGGM GLPRLGGHGG DGGDVWVVAK
60 70 80 90 100
KDTRLKQIKD KHPDKRFIAG VGSNSSIQAL RGAKGEDVEV FAPTGISVTS
110 120 130 140 150
DHGRMLGELN REGDKLLVAK GGRGGSPQSG FLPNKGQTRN IRLDLKLIAD
160 170 180 190 200
FGLVGFPNAG KSSLLTALSH AKPKIANYPF TTIKPEIGKV MYDDHKQVSV
210 220 230 240 250
ADLPGLIEGA HVNKGMGHKF LKHVERTKQL MFVVDVCGFQ LASKTPFRSA
260 270 280 290 300
FETVLLLSKE LELYKEELLS KPAILVINKM DLPEAQSHFQ ELEAQLENQG
310 320 330 340 350
ESIHLFSEDV IPKSLMHFTH IVPVSAMTGH GLPLLKSLIR QSLEEQDTID
360 370 380
TEAQRSQKIL ELRREIPSSS IPSWGLPQPT
Length:380
Mass (Da):41,757
Last modified:August 16, 2004 - v1
Checksum:i827F85ED6D3CCCBD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC076017 mRNA. Translation: AAH76017.1.
RefSeqiNP_001002454.1. NM_001002454.1.
UniGeneiDr.83150.

Genome annotation databases

EnsembliENSDART00000058970; ENSDARP00000058969; ENSDARG00000040300.
GeneIDi436727.
KEGGidre:436727.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC076017 mRNA. Translation: AAH76017.1.
RefSeqiNP_001002454.1. NM_001002454.1.
UniGeneiDr.83150.

3D structure databases

ProteinModelPortaliQ6DHF7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000058969.

Proteomic databases

PaxDbiQ6DHF7.
PRIDEiQ6DHF7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000058970; ENSDARP00000058969; ENSDARG00000040300.
GeneIDi436727.
KEGGidre:436727.

Organism-specific databases

CTDi85865.
ZFINiZDB-GENE-040718-153. gtpbp10.

Phylogenomic databases

eggNOGiKOG1489. Eukaryota.
COG0536. LUCA.
GeneTreeiENSGT00530000063429.
HOGENOMiHOG000019084.
HOVERGENiHBG104309.
InParanoidiQ6DHF7.
OMAiNLWISDT.
OrthoDBiEOG7DJSMM.
PhylomeDBiQ6DHF7.
TreeFamiTF314774.

Miscellaneous databases

PROiQ6DHF7.

Gene expression databases

BgeeiQ6DHF7.

Family and domain databases

Gene3Di2.70.210.12. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR031167. G_OBG.
IPR014100. GTP-bd_Obg/CgtA.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11702:SF3. PTHR11702:SF3. 1 hit.
PfamiPF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFiPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
PROSITEiPS51710. G_OBG. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiGTPBA_DANRE
AccessioniPrimary (citable) accession number: Q6DHF7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: August 16, 2004
Last modified: June 8, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.