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Protein

Density-regulated protein

Gene

denr

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Density-regulated protein
Short name:
DRP
Gene namesi
Name:denr
ORF Names:zgc:92629
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 10

Organism-specific databases

ZFINiZDB-GENE-040718-450 denr

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001306041 – 208Density-regulated proteinAdd BLAST208

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei9Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ6DH65

PTM databases

iPTMnetiQ6DH65

Expressioni

Gene expression databases

BgeeiENSDARG00000037229

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000054152

Structurei

3D structure databases

ProteinModelPortaliQ6DH65
SMRiQ6DH65
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini125 – 192SUI1PROSITE-ProRule annotationAdd BLAST68

Sequence similaritiesi

Belongs to the DENR family.Curated

Phylogenomic databases

eggNOGiKOG3239 Eukaryota
COG0023 LUCA
GeneTreeiENSGT00390000014349
HOGENOMiHOG000237611
HOVERGENiHBG005471
InParanoidiQ6DH65
OMAiSGGHDCK
OrthoDBiEOG091G0R9X
PhylomeDBiQ6DH65
TreeFamiTF105912

Family and domain databases

InterProiView protein in InterPro
IPR005873 Drp1
IPR001950 SUI1
IPR005872 SUI1_arc_bac
IPR036877 SUI1_dom_sf
PANTHERiPTHR12789 PTHR12789, 1 hit
PfamiView protein in Pfam
PF01253 SUI1, 1 hit
SUPFAMiSSF55159 SSF55159, 2 hits
TIGRFAMsiTIGR01159 DRP1, 1 hit
PROSITEiView protein in PROSITE
PS50296 SUI1, 1 hit

Sequencei

Sequence statusi: Complete.

Q6DH65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTENAESG SPENKVDRAD PDAKYPLKVL YCGVCSLPAE YCEYMPEPAK
60 70 80 90 100
CKQWLEKNFP DVFAKLTLGT APKQESKGGG GGEDGGGGRG RGEAPPAGEE
110 120 130 140 150
EEKKKQKRGG RGQIKQKKKT VPQKVTIAKI PRAKKKYVTR VCGLATFDIE
160 170 180 190 200
LKEAQRFFAQ KFSCGASVTA EDEIIIQGDF TDDIIDVIQE KWPEVDDDSI

DDLGEVKK
Length:208
Mass (Da):22,804
Last modified:August 16, 2004 - v1
Checksum:i8AD1E48F5E7F9D53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC076117 mRNA Translation: AAH76117.1
BC095896 mRNA Translation: AAH95896.1
RefSeqiNP_001002697.1, NM_001002697.2
UniGeneiDr.11982

Genome annotation databases

EnsembliENSDART00000054153; ENSDARP00000054152; ENSDARG00000037229
GeneIDi436970
KEGGidre:436970

Similar proteinsi

Entry informationi

Entry nameiDENR_DANRE
AccessioniPrimary (citable) accession number: Q6DH65
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: August 16, 2004
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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