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Q6DH46 (ACPL2_DANRE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acid phosphatase-like protein 2

EC=3.1.3.2
Gene names
Name:acpl2
ORF Names:zgc:92652
OrganismDanio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]
Taxonomic identifier7955 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Protein attributes

Sequence length503 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Subcellular location

Secreted Potential.

Sequence similarities

Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionHydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionacid phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 503480Acid phosphatase-like protein 2
PRO_0000314927

Sites

Active site981Nucleophile By similarity
Active site3961Proton donor By similarity

Amino acid modifications

Glycosylation731N-linked (GlcNAc...) Potential
Glycosylation3651N-linked (GlcNAc...) Potential
Glycosylation4901N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q6DH46 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 6A7AC989468E8D12

FASTA50357,021
        10         20         30         40         50         60 
MLARSRFILV LVVGALLAVL SFSLQYLHLI PTNPVAEQRS AGRSRKRVNP VLHTDPPAPD 

        70         80         90        100        110        120 
PIRDTHQYCN YPNLTEHGWE GHCPPDYKLL SVQVMIRHGD RFPLYSIPKT KKPTIDCILS 

       130        140        150        160        170        180 
EKRKPSHPLL ASFISHMALG GRGHWDASLG SLPRLPSHST CEMGELTQTG VVRQLKNGDH 

       190        200        210        220        230        240 
LRQAYISRHN LLAADWLPRQ LWAETTGKSR TLQSGLAFLF GFLPHFDWSR LTVRQQWSTL 

       250        260        270        280        290        300 
FCGQSCDCPA RNRYLDQEQR RQYRQRIADA ELERTYVTMA KTLGVATKTL RAANPVDALL 

       310        320        330        340        350        360 
CHFCHGLPFP CSSTQTSSNA PDEGACLTLE HFAVIRRQQK DDELERREAG LYRRYAVLAA 

       370        380        390        400        410        420 
HPYLNRSAAR LERIARGSQM RKSKEDAVFA LASAHDVTMA PLLSALGLEG AGFPKFAARL 

       430        440        450        460        470        480 
VFELWSSPET KERRSDRKLD NMFIRVLYNG EDLTFDTAFC REHNRRSTQP LCPLGNFLSF 

       490        500 
VRKDMFSVVN ATSYQQACHQ TVL 

« Hide

References

[1]NIH - Zebrafish Gene Collection (ZGC) project
Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Larval eye.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC076136 mRNA. Translation: AAH76136.1.
RefSeqNP_001002430.1. NM_001002430.1.
UniGeneDr.108758.

3D structure databases

ProteinModelPortalQ6DH46.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7955.ENSDARP00000059507.

Proteomic databases

PRIDEQ6DH46.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID436703.
KEGGdre:436703.

Organism-specific databases

CTD92370.
ZFINZDB-GENE-040718-127. acpl2.

Phylogenomic databases

eggNOGNOG321954.
HOGENOMHOG000033787.
HOVERGENHBG106056.
InParanoidQ6DH46.
PhylomeDBQ6DH46.

Family and domain databases

InterProIPR000560. His_Pase_superF_clade-2.
[Graphical view]
PfamPF00328. His_Phos_2. 1 hit.
[Graphical view]
PROSITEPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20831146.
PROQ6DH46.

Entry information

Entry nameACPL2_DANRE
AccessionPrimary (citable) accession number: Q6DH46
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 16, 2004
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families