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Q6DH46

- ACPL2_DANRE

UniProt

Q6DH46 - ACPL2_DANRE

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Protein
Acid phosphatase-like protein 2
Gene
acpl2, zgc:92652
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei98 – 981Nucleophile By similarity
Active sitei396 – 3961Proton donor By similarity

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Acid phosphatase-like protein 2 (EC:3.1.3.2)
Gene namesi
Name:acpl2
ORF Names:zgc:92652
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Unplaced

Organism-specific databases

ZFINiZDB-GENE-040718-127. pxylp1.

Subcellular locationi

Secreted Reviewed prediction

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323 Reviewed prediction
Add
BLAST
Chaini24 – 503480Acid phosphatase-like protein 2
PRO_0000314927Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi73 – 731N-linked (GlcNAc...) Reviewed prediction
Glycosylationi365 – 3651N-linked (GlcNAc...) Reviewed prediction
Glycosylationi490 – 4901N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ6DH46.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000059507.

Structurei

3D structure databases

ProteinModelPortaliQ6DH46.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG321954.
HOGENOMiHOG000033787.
HOVERGENiHBG106056.
InParanoidiQ6DH46.
PhylomeDBiQ6DH46.

Family and domain databases

Gene3Di3.40.50.1240. 2 hits.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6DH46-1 [UniParc]FASTAAdd to Basket

« Hide

MLARSRFILV LVVGALLAVL SFSLQYLHLI PTNPVAEQRS AGRSRKRVNP    50
VLHTDPPAPD PIRDTHQYCN YPNLTEHGWE GHCPPDYKLL SVQVMIRHGD 100
RFPLYSIPKT KKPTIDCILS EKRKPSHPLL ASFISHMALG GRGHWDASLG 150
SLPRLPSHST CEMGELTQTG VVRQLKNGDH LRQAYISRHN LLAADWLPRQ 200
LWAETTGKSR TLQSGLAFLF GFLPHFDWSR LTVRQQWSTL FCGQSCDCPA 250
RNRYLDQEQR RQYRQRIADA ELERTYVTMA KTLGVATKTL RAANPVDALL 300
CHFCHGLPFP CSSTQTSSNA PDEGACLTLE HFAVIRRQQK DDELERREAG 350
LYRRYAVLAA HPYLNRSAAR LERIARGSQM RKSKEDAVFA LASAHDVTMA 400
PLLSALGLEG AGFPKFAARL VFELWSSPET KERRSDRKLD NMFIRVLYNG 450
EDLTFDTAFC REHNRRSTQP LCPLGNFLSF VRKDMFSVVN ATSYQQACHQ 500
TVL 503
Length:503
Mass (Da):57,021
Last modified:August 16, 2004 - v1
Checksum:i6A7AC989468E8D12
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC076136 mRNA. Translation: AAH76136.1.
RefSeqiNP_001002430.1. NM_001002430.1.
UniGeneiDr.108758.

Genome annotation databases

GeneIDi436703.
KEGGidre:436703.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC076136 mRNA. Translation: AAH76136.1 .
RefSeqi NP_001002430.1. NM_001002430.1.
UniGenei Dr.108758.

3D structure databases

ProteinModelPortali Q6DH46.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7955.ENSDARP00000059507.

Proteomic databases

PRIDEi Q6DH46.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 436703.
KEGGi dre:436703.

Organism-specific databases

CTDi 92370.
ZFINi ZDB-GENE-040718-127. pxylp1.

Phylogenomic databases

eggNOGi NOG321954.
HOGENOMi HOG000033787.
HOVERGENi HBG106056.
InParanoidi Q6DH46.
PhylomeDBi Q6DH46.

Miscellaneous databases

NextBioi 20831146.
PROi Q6DH46.

Family and domain databases

Gene3Di 3.40.50.1240. 2 hits.
InterProi IPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view ]
Pfami PF00328. His_Phos_2. 1 hit.
[Graphical view ]
SUPFAMi SSF53254. SSF53254. 1 hit.
PROSITEi PS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Larval eye.

Entry informationi

Entry nameiACPL2_DANRE
AccessioniPrimary (citable) accession number: Q6DH46
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 16, 2004
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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