Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q6DH46

- ACPL2_DANRE

UniProt

Q6DH46 - ACPL2_DANRE

Protein

Acid phosphatase-like protein 2

Gene

acpl2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (16 Aug 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    A phosphate monoester + H2O = an alcohol + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei98 – 981NucleophileBy similarity
    Active sitei396 – 3961Proton donorBy similarity

    GO - Molecular functioni

    1. acid phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acid phosphatase-like protein 2 (EC:3.1.3.2)
    Gene namesi
    Name:acpl2
    ORF Names:zgc:92652
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
    ProteomesiUP000000437: Unplaced

    Organism-specific databases

    ZFINiZDB-GENE-040718-127. pxylp1.

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2323Sequence AnalysisAdd
    BLAST
    Chaini24 – 503480Acid phosphatase-like protein 2PRO_0000314927Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi73 – 731N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi365 – 3651N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi490 – 4901N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiQ6DH46.

    Interactioni

    Protein-protein interaction databases

    STRINGi7955.ENSDARP00000059507.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6DH46.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histidine acid phosphatase family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG321954.
    HOGENOMiHOG000033787.
    HOVERGENiHBG106056.
    InParanoidiQ6DH46.
    PhylomeDBiQ6DH46.

    Family and domain databases

    Gene3Di3.40.50.1240. 2 hits.
    InterProiIPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    [Graphical view]
    PfamiPF00328. His_Phos_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF53254. SSF53254. 1 hit.
    PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q6DH46-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLARSRFILV LVVGALLAVL SFSLQYLHLI PTNPVAEQRS AGRSRKRVNP    50
    VLHTDPPAPD PIRDTHQYCN YPNLTEHGWE GHCPPDYKLL SVQVMIRHGD 100
    RFPLYSIPKT KKPTIDCILS EKRKPSHPLL ASFISHMALG GRGHWDASLG 150
    SLPRLPSHST CEMGELTQTG VVRQLKNGDH LRQAYISRHN LLAADWLPRQ 200
    LWAETTGKSR TLQSGLAFLF GFLPHFDWSR LTVRQQWSTL FCGQSCDCPA 250
    RNRYLDQEQR RQYRQRIADA ELERTYVTMA KTLGVATKTL RAANPVDALL 300
    CHFCHGLPFP CSSTQTSSNA PDEGACLTLE HFAVIRRQQK DDELERREAG 350
    LYRRYAVLAA HPYLNRSAAR LERIARGSQM RKSKEDAVFA LASAHDVTMA 400
    PLLSALGLEG AGFPKFAARL VFELWSSPET KERRSDRKLD NMFIRVLYNG 450
    EDLTFDTAFC REHNRRSTQP LCPLGNFLSF VRKDMFSVVN ATSYQQACHQ 500
    TVL 503
    Length:503
    Mass (Da):57,021
    Last modified:August 16, 2004 - v1
    Checksum:i6A7AC989468E8D12
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC076136 mRNA. Translation: AAH76136.1.
    RefSeqiNP_001002430.1. NM_001002430.1.
    UniGeneiDr.108758.

    Genome annotation databases

    GeneIDi436703.
    KEGGidre:436703.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC076136 mRNA. Translation: AAH76136.1 .
    RefSeqi NP_001002430.1. NM_001002430.1.
    UniGenei Dr.108758.

    3D structure databases

    ProteinModelPortali Q6DH46.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7955.ENSDARP00000059507.

    Proteomic databases

    PRIDEi Q6DH46.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 436703.
    KEGGi dre:436703.

    Organism-specific databases

    CTDi 92370.
    ZFINi ZDB-GENE-040718-127. pxylp1.

    Phylogenomic databases

    eggNOGi NOG321954.
    HOGENOMi HOG000033787.
    HOVERGENi HBG106056.
    InParanoidi Q6DH46.
    PhylomeDBi Q6DH46.

    Miscellaneous databases

    NextBioi 20831146.
    PROi Q6DH46.

    Family and domain databases

    Gene3Di 3.40.50.1240. 2 hits.
    InterProi IPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    [Graphical view ]
    Pfami PF00328. His_Phos_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53254. SSF53254. 1 hit.
    PROSITEi PS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Larval eye.

    Entry informationi

    Entry nameiACPL2_DANRE
    AccessioniPrimary (citable) accession number: Q6DH46
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: August 16, 2004
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3