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Protein

Glutathione S-transferase kappa

Gene

gstk1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei16NucleophileUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-DRE-156590. Glutathione conjugation.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase kappaUniRule annotation (EC:2.5.1.18UniRule annotation)
Gene namesi
Name:gstk1Imported
ORF Names:zgc:92763Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 16

Organism-specific databases

ZFINiZDB-GENE-040718-298. gstk1.

Expressioni

Gene expression databases

BgeeiENSDARG00000056510.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000035103.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 213DSBAInterPro annotationAdd BLAST207

Sequence similaritiesi

Belongs to the GST superfamily. Kappa family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IJK9. Eukaryota.
COG3917. LUCA.
GeneTreeiENSGT00440000033697.
HOGENOMiHOG000219769.
HOVERGENiHBG051852.
KOiK13299.
OMAiETEGFWG.
OrthoDBiEOG091G0LCM.
TreeFamiTF105323.

Family and domain databases

InterProiView protein in InterPro
IPR001853. DSBA-like_thioredoxin_dom.
IPR014440. HCCAis_GSTk.
IPR036249. Thioredoxin-like_sf.
PfamiView protein in Pfam
PF01323. DSBA. 1 hit.
PIRSFiPIRSF006386. HCCAis_GSTk. 1 hit.
SUPFAMiSSF52833. SSF52833. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6DGU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGSRKVVEL FYDVVSPYSW LAFEVLCRYR NVWNIDLKLK PAFLGAVMHD
60 70 80 90 100
SGNRPPGMIP NKFLYMTSDL KHVSEYFGVP VRQPSNVFET MFEKGSLKAM
110 120 130 140 150
RFVTAVAEKE KEGDVKLERV SRELWNRIWS NDQDITLPAS FAEAGLKAGL
160 170 180 190 200
TASEVDELLT LATSQPIKDK LKSVTSEAIK YKCFGFPTIV CHVDGKPEIF
210 220
FGSDRFEVMA HIIGEKWMGP NPVKPMAKM
Length:229
Mass (Da):25,907
Last modified:August 16, 2004 - v1
Checksum:i6BA2C27DDA0C1B05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR854927 Genomic DNA. No translation available.
BC076240 mRNA. Translation: AAH76240.1.
RefSeqiNP_001002560.1. NM_001002560.1.
XP_005158401.1. XM_005158344.3.
UniGeneiDr.76489.

Genome annotation databases

EnsembliENSDART00000030282; ENSDARP00000035103; ENSDARG00000056510.
GeneIDi436833.
KEGGidre:436833.

Similar proteinsi

Entry informationi

Entry nameiQ6DGU9_DANRE
AccessioniPrimary (citable) accession number: Q6DGU9
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: October 25, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported