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Q6DGF9 (ACBD4_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acyl-CoA-binding domain-containing protein 4
Gene names
Name:Acbd4
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length326 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA esters By similarity.

Sequence similarities

Contains 1 ACB (acyl-CoA-binding) domain.

Ontologies

Keywords
   LigandLipid-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionfatty-acyl-CoA binding

Inferred from electronic annotation. Source: InterPro

lipid binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 326326Acyl-CoA-binding domain-containing protein 4
PRO_0000214034

Regions

Domain10 – 9990ACB
Region21 – 3010Acyl-CoA binding By similarity
Region41 – 455Acyl-CoA binding By similarity

Sites

Binding site671Acyl-CoA By similarity
Binding site861Acyl-CoA By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6DGF9 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 9936AC0B4FC13C61

FASTA32637,316
        10         20         30         40         50         60 
MGTEKEEPDC QKQFQAAVSV IQNLPKNGSY RPSYEEMLRF YSYYKQATAG PCLVPRPGFW 

        70         80         90        100        110        120 
DPIGRYKWDA WNSLGKMSRE EAMSAYITEM KLVAQKVIDT VPLGEVAEDM FGYFEPLYQV 

       130        140        150        160        170        180 
IPDMPRPPET FLRRVTGWQE PAVNRDVQAA PEPSHPPKEP APPSPESRLP RDLDLEVFCD 

       190        200        210        220        230        240 
SVEQLEPELV RVPVLSPVPA ESELPHLHTG TGDSAQRVWA EQKEAAGREL TTRSSPESPE 

       250        260        270        280        290        300 
GFGGSLMGPQ ELDRWLVGTV QAMQESMKDV HRRLQILESK PQPLEQQRSP RTRPWPLGLS 

       310        320 
TPTLLFFILW PFVVQWLFRQ FRTQRR 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Kidney.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC076387 mRNA. Translation: AAH76387.1.
RefSeqNP_001012013.1. NM_001012013.1.
XP_006247572.1. XM_006247510.1.
UniGeneRn.18284.

3D structure databases

ProteinModelPortalQ6DGF9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000004163.

PTM databases

PhosphoSiteQ6DGF9.

Proteomic databases

PRIDEQ6DGF9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000004163; ENSRNOP00000004163; ENSRNOG00000003108.
GeneID303577.
KEGGrno:303577.
UCSCRGD:1308404. rat.

Organism-specific databases

CTD79777.
RGD1308404. Acbd4.

Phylogenomic databases

eggNOGCOG4281.
GeneTreeENSGT00730000110900.
HOGENOMHOG000231479.
HOVERGENHBG028530.
InParanoidQ6DGF9.
OMAWLVGTVR.
OrthoDBEOG7TJ3JP.
PhylomeDBQ6DGF9.
TreeFamTF319446.

Gene expression databases

GenevestigatorQ6DGF9.

Family and domain databases

Gene3D1.20.80.10. 1 hit.
InterProIPR022408. Acyl-CoA-binding_prot_CS.
IPR000582. Acyl-CoA-binding_protein.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
[Graphical view]
PfamPF00887. ACBP. 1 hit.
[Graphical view]
PRINTSPR00689. ACOABINDINGP.
SUPFAMSSF47027. SSF47027. 1 hit.
PROSITEPS00880. ACB_1. 1 hit.
PS51228. ACB_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio651653.

Entry information

Entry nameACBD4_RAT
AccessionPrimary (citable) accession number: Q6DGF9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: August 16, 2004
Last modified: April 16, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families