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Q6DGF9

- ACBD4_RAT

UniProt

Q6DGF9 - ACBD4_RAT

Protein

Acyl-CoA-binding domain-containing protein 4

Gene

Acbd4

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (16 Aug 2004)
      Previous versions | rss
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    Functioni

    Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA esters.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei67 – 671Acyl-CoABy similarity
    Binding sitei86 – 861Acyl-CoABy similarity

    GO - Molecular functioni

    1. fatty-acyl-CoA binding Source: InterPro
    2. lipid binding Source: UniProtKB-KW

    Keywords - Ligandi

    Lipid-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acyl-CoA-binding domain-containing protein 4
    Gene namesi
    Name:Acbd4
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 10

    Organism-specific databases

    RGDi1308404. Acbd4.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 326326Acyl-CoA-binding domain-containing protein 4PRO_0000214034Add
    BLAST

    Proteomic databases

    PRIDEiQ6DGF9.

    PTM databases

    PhosphoSiteiQ6DGF9.

    Expressioni

    Gene expression databases

    GenevestigatoriQ6DGF9.

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000004163.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6DGF9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 9990ACBPROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni21 – 3010Acyl-CoA bindingBy similarity
    Regioni41 – 455Acyl-CoA bindingBy similarity

    Sequence similaritiesi

    Contains 1 ACB (acyl-CoA-binding) domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG4281.
    GeneTreeiENSGT00730000110900.
    HOGENOMiHOG000231479.
    HOVERGENiHBG028530.
    InParanoidiQ6DGF9.
    OMAiWLVGTVR.
    OrthoDBiEOG7TJ3JP.
    PhylomeDBiQ6DGF9.
    TreeFamiTF319446.

    Family and domain databases

    Gene3Di1.20.80.10. 1 hit.
    InterProiIPR022408. Acyl-CoA-binding_prot_CS.
    IPR000582. Acyl-CoA-binding_protein.
    IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
    [Graphical view]
    PfamiPF00887. ACBP. 1 hit.
    [Graphical view]
    PRINTSiPR00689. ACOABINDINGP.
    SUPFAMiSSF47027. SSF47027. 1 hit.
    PROSITEiPS00880. ACB_1. 1 hit.
    PS51228. ACB_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6DGF9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGTEKEEPDC QKQFQAAVSV IQNLPKNGSY RPSYEEMLRF YSYYKQATAG    50
    PCLVPRPGFW DPIGRYKWDA WNSLGKMSRE EAMSAYITEM KLVAQKVIDT 100
    VPLGEVAEDM FGYFEPLYQV IPDMPRPPET FLRRVTGWQE PAVNRDVQAA 150
    PEPSHPPKEP APPSPESRLP RDLDLEVFCD SVEQLEPELV RVPVLSPVPA 200
    ESELPHLHTG TGDSAQRVWA EQKEAAGREL TTRSSPESPE GFGGSLMGPQ 250
    ELDRWLVGTV QAMQESMKDV HRRLQILESK PQPLEQQRSP RTRPWPLGLS 300
    TPTLLFFILW PFVVQWLFRQ FRTQRR 326
    Length:326
    Mass (Da):37,316
    Last modified:August 16, 2004 - v1
    Checksum:i9936AC0B4FC13C61
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC076387 mRNA. Translation: AAH76387.1.
    RefSeqiNP_001012013.1. NM_001012013.1.
    XP_006247572.1. XM_006247510.1.
    UniGeneiRn.18284.

    Genome annotation databases

    EnsembliENSRNOT00000004163; ENSRNOP00000004163; ENSRNOG00000003108.
    GeneIDi303577.
    KEGGirno:303577.
    UCSCiRGD:1308404. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC076387 mRNA. Translation: AAH76387.1 .
    RefSeqi NP_001012013.1. NM_001012013.1.
    XP_006247572.1. XM_006247510.1.
    UniGenei Rn.18284.

    3D structure databases

    ProteinModelPortali Q6DGF9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000004163.

    PTM databases

    PhosphoSitei Q6DGF9.

    Proteomic databases

    PRIDEi Q6DGF9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000004163 ; ENSRNOP00000004163 ; ENSRNOG00000003108 .
    GeneIDi 303577.
    KEGGi rno:303577.
    UCSCi RGD:1308404. rat.

    Organism-specific databases

    CTDi 79777.
    RGDi 1308404. Acbd4.

    Phylogenomic databases

    eggNOGi COG4281.
    GeneTreei ENSGT00730000110900.
    HOGENOMi HOG000231479.
    HOVERGENi HBG028530.
    InParanoidi Q6DGF9.
    OMAi WLVGTVR.
    OrthoDBi EOG7TJ3JP.
    PhylomeDBi Q6DGF9.
    TreeFami TF319446.

    Miscellaneous databases

    NextBioi 651653.

    Gene expression databases

    Genevestigatori Q6DGF9.

    Family and domain databases

    Gene3Di 1.20.80.10. 1 hit.
    InterProi IPR022408. Acyl-CoA-binding_prot_CS.
    IPR000582. Acyl-CoA-binding_protein.
    IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
    [Graphical view ]
    Pfami PF00887. ACBP. 1 hit.
    [Graphical view ]
    PRINTSi PR00689. ACOABINDINGP.
    SUPFAMi SSF47027. SSF47027. 1 hit.
    PROSITEi PS00880. ACB_1. 1 hit.
    PS51228. ACB_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Kidney.

    Entry informationi

    Entry nameiACBD4_RAT
    AccessioniPrimary (citable) accession number: Q6DGF9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 7, 2005
    Last sequence update: August 16, 2004
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3