Q6DGF9 (ACBD4_RAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acyl-CoA-binding domain-containing protein 4

Gene names

Name:

Acbd4

Organism

Rattus norvegicus (Rat) [Reference proteome]

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	326 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA esters By similarity.
Sequence similarities	Contains 1 ACB (acyl-CoA-binding) domain.

Ontologies

Keywords
Ligand	Lipid-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	fatty-acyl-CoA binding Inferred from electronic annotation. Source: InterPro lipid binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 326	326	Acyl-CoA-binding domain-containing protein 4		PRO_0000214034
Regions
	Domain	10 – 99	90	ACB
	Region	21 – 30	10	Acyl-CoA binding By similarity
	Region	41 – 45	5	Acyl-CoA binding By similarity
Sites
	Binding site	67	1	Acyl-CoA By similarity
	Binding site	86	1	Acyl-CoA By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6DGF9 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 9936AC0B4FC13C61	FASTA	326	37,316
	10 20 30 40 50 60 MGTEKEEPDC QKQFQAAVSV IQNLPKNGSY RPSYEEMLRF YSYYKQATAG PCLVPRPGFW 70 80 90 100 110 120 DPIGRYKWDA WNSLGKMSRE EAMSAYITEM KLVAQKVIDT VPLGEVAEDM FGYFEPLYQV 130 140 150 160 170 180 IPDMPRPPET FLRRVTGWQE PAVNRDVQAA PEPSHPPKEP APPSPESRLP RDLDLEVFCD 190 200 210 220 230 240 SVEQLEPELV RVPVLSPVPA ESELPHLHTG TGDSAQRVWA EQKEAAGREL TTRSSPESPE 250 260 270 280 290 300 GFGGSLMGPQ ELDRWLVGTV QAMQESMKDV HRRLQILESK PQPLEQQRSP RTRPWPLGLS 310 320 TPTLLFFILW PFVVQWLFRQ FRTQRR

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC076387 mRNA. Translation: AAH76387.1.
IPI	IPI00464904.
RefSeq	NP_001012013.1. NM_001012013.1.
UniGene	Rn.18284.
3D structure databases
ProteinModelPortal	Q6DGF9.
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000004163.
PTM databases
PhosphoSite	Q6DGF9.
Proteomic databases
PRIDE	Q6DGF9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000004163; ENSRNOP00000004163; ENSRNOG00000003108.
GeneID	303577.
KEGG	rno:303577.
UCSC	RGD:1308404. rat.
Organism-specific databases
CTD	79777.
RGD	1308404. Acbd4.
Phylogenomic databases
eggNOG	COG4281.
GeneTree	ENSGT00680000099745.
HOGENOM	HOG000231479.
HOVERGEN	HBG028530.
InParanoid	Q6DGF9.
OMA	WLVGTVR.
OrthoDB	EOG4GF3FX.
Gene expression databases
ArrayExpress	Q6DGF9.
Genevestigator	Q6DGF9.
GermOnline	ENSRNOG00000003108. Rattus norvegicus.
Family and domain databases
Gene3D	1.20.80.10. 1 hit.
InterPro	IPR022408. Acyl-CoA-binding_prot_CS. IPR000582. Acyl-CoA-binding_protein. IPR014352. FERM/acyl-CoA-bd_prot_3-hlx. [Graphical view]
Pfam	PF00887. ACBP. 1 hit. [Graphical view]
PRINTS	PR00689. ACOABINDINGP.
SUPFAM	SSF47027. ACBP. 1 hit.
PROSITE	PS00880. ACB_1. 1 hit. PS51228. ACB_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	651653.

Entry information

Entry name

ACBD4_RAT

Accession

Primary (citable) accession number: Q6DGF9

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	August 16, 2004
Last modified:	April 3, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program