Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Retinoic acid receptor, beta

Gene

Rarb

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi78 – 153Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Retinoic acid receptor, betaImported
Submitted name:
Retinoic acid receptor, beta, isoform CRA_aImported
Gene namesi
Name:RarbImported
ORF Names:mCG_17385Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97857 Rarb

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000017491
ExpressionAtlasiQ6DFX0 baseline and differential

Structurei

3D structure databases

SMRiQ6DFX0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 153Nuclear receptorInterPro annotationAdd BLAST76
Domaini176 – 410NR LBDInterPro annotationAdd BLAST235

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili170 – 190Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
HOVERGENiHBG005606
KOiK08528
OMAiSVPGFKM
OrthoDBiEOG091G0XCQ

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR003078 Retinoic_acid_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01292 RETNOICACIDR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6DFX0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDCMDVLSV SPGQILDFYT ASPSSCMLQE KALKACLSGF TQAEWQHRHT
60 70 80 90 100
AQSIETQSTS SEELVPSPPS PLPPPRVYKP CFVCQDKSSG YHYGVSACEG
110 120 130 140 150
CKGFFRRSIQ KNMIYTCHRD KNCVINKVTR NRCQYCRLQK CFEVGMSKES
160 170 180 190 200
VRNDRNKKKK EPSKQECTES YEMTAELDDL TEKIRKAHQE TFPSLCQLGK
210 220 230 240 250
YTTNSSADHR VRLDLGLWDK FSELATKCII KIVEFAKRLP GFTGLTIADQ
260 270 280 290 300
ITLLKAACLD ILILRICTRY TPEQDTMTFS DGLTLNRTQM HNAGFGPLTD
310 320 330 340 350
LVFTFANQLL PLEMDDTETG LLSAICLICG DRQDLEEPTK VDKLQEPLLE
360 370 380 390 400
ALKIYIRKRR PSKPHMFPKI LMKITDLRSI SAKGAERVIT LKMEIPGSMP
410 420 430 440
PLIQEMLENS EGHEPLTPSS SGNIAEHSPS VSPSSVENSG VSQSPLLQ
Length:448
Mass (Da):50,322
Last modified:May 10, 2005 - v1
Checksum:iFA4EA32326EAB900
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC076597 mRNA Translation: AAH76597.1
CH466579 Genomic DNA Translation: EDL20643.1
RefSeqiNP_001276689.1, NM_001289760.1
NP_001276690.1, NM_001289761.1
NP_001276691.1, NM_001289762.1
NP_035373.1, NM_011243.2
UniGeneiMm.259318

Genome annotation databases

GeneIDi218772
KEGGimmu:218772
UCSCiuc007she.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ6DFX0_MOUSE
AccessioniPrimary (citable) accession number: Q6DFX0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health