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Protein

Cyclin-dependent kinases regulatory subunit

Gene

cks1b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell divisionUniRule annotation

Enzyme and pathway databases

ReactomeiR-DRE-187577. SCF(Skp2)-mediated degradation of p27/p21.
R-DRE-69231. Cyclin D associated events in G1.

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinases regulatory subunitUniRule annotation
Gene namesi
Name:cks1bImported
Synonyms:zgc:101026Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 19

Organism-specific databases

ZFINiZDB-GENE-040801-112. cks1b.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSDARG00000007971.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000003357.

Family & Domainsi

Sequence similaritiesi

Belongs to the CKS family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3484. Eukaryota.
ENOG4111UAN. LUCA.
GeneTreeiENSGT00390000011006.
HOGENOMiHOG000157009.
HOVERGENiHBG003626.
KOiK02219.
OMAiLMTENEW.
OrthoDBiEOG091G18GQ.
TreeFamiTF101142.

Family and domain databases

Gene3Di3.30.170.10. 1 hit.
InterProiView protein in InterPro
IPR000789. Cyclin-dep_kinase_reg-sub.
PfamiView protein in Pfam
PF01111. CKS. 1 hit.
PRINTSiPR00296. CYCLINKINASE.
SMARTiView protein in SMART
SM01084. CKS. 1 hit.
SUPFAMiSSF55637. SSF55637. 1 hit.
PROSITEiView protein in PROSITE
PS00944. CKS_1. 1 hit.
PS00945. CKS_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6DEL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHKQIYYSD KYDDDKFEYR HVMLPKDIAK RVPKTHLMSE TEWRNLGVQQ
60 70
SQGWVHYMIH QPEPHILLFR RPLPVAQSH
Length:79
Mass (Da):9,614
Last modified:August 16, 2004 - v1
Checksum:i90B3923140BA3C8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR628394 Genomic DNA. No translation available.
BC077092 mRNA. Translation: AAH77092.1.
RefSeqiNP_001003593.1. NM_001003593.3.
UniGeneiDr.119277.

Genome annotation databases

EnsembliENSDART00000026276; ENSDARP00000003357; ENSDARG00000007971.
GeneIDi445199.
KEGGidre:445199.

Similar proteinsi

Entry informationi

Entry nameiQ6DEL8_DANRE
AccessioniPrimary (citable) accession number: Q6DEL8
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: June 7, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported