ID   Q6DDA5_XENTR            Unreviewed;       147 AA.
AC   Q6DDA5;
DT   16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT   16-AUG-2004, sequence version 1.
DT   27-MAR-2024, entry version 85.
DE   SubName: Full=Microsomal glutathione S-transferase 3 {ECO:0000313|EMBL:AAH77689.1, ECO:0000313|RefSeq:NP_001006890.1};
DE            EC=2.5.1.18 {ECO:0000313|RefSeq:NP_001006890.1};
GN   Name=mgst3 {ECO:0000313|EMBL:AAH77689.1,
GN   ECO:0000313|RefSeq:NP_001006890.1,
GN   ECO:0000313|Xenbase:XB-GENE-976812};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364 {ECO:0000313|EMBL:AAH77689.1};
RN   [1] {ECO:0000313|RefSeq:NP_001006890.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12454917; DOI=10.1002/dvdy.10174;
RA   Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA   Richardson P.;
RT   "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT   initiative.";
RL   Dev. Dyn. 225:384-391(2002).
RN   [2] {ECO:0000313|EMBL:AAH77689.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo {ECO:0000313|EMBL:AAH77689.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|RefSeq:NP_001006890.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; BC077689; AAH77689.1; -; mRNA.
DR   RefSeq; NP_001006890.1; NM_001006889.2.
DR   GeneID; 448730; -.
DR   KEGG; xtr:448730; -.
DR   AGR; Xenbase:XB-GENE-976812; -.
DR   CTD; 4259; -.
DR   Xenbase; XB-GENE-976812; mgst3.
DR   OMA; ACQHLGW; -.
DR   OrthoDB; 5487436at2759; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006691; P:leukotriene metabolic process; IEA:UniProt.
DR   Gene3D; 1.20.120.550; Membrane associated eicosanoid/glutathione metabolism-like domain; 1.
DR   InterPro; IPR023352; MAPEG-like_dom_sf.
DR   InterPro; IPR001129; Membr-assoc_MAPEG.
DR   PANTHER; PTHR10250; MICROSOMAL GLUTATHIONE S-TRANSFERASE; 1.
DR   PANTHER; PTHR10250:SF27; MICROSOMAL GLUTATHIONE S-TRANSFERASE 3; 1.
DR   Pfam; PF01124; MAPEG; 1.
DR   SUPFAM; SSF161084; MAPEG domain-like; 1.
PE   2: Evidence at transcript level;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW   Transferase {ECO:0000313|EMBL:AAH77689.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   147 AA;  16210 MW;  0819E4D703C26C45 CRC64;
     MVVLSKEYGY VVLTGAASFI MVTHLAINVG KARKQYKVEY PKMYSDDPEN GNIFNCIQRA
     HQNTLESYPP FLFFLAVGGL THPRATSALG VAWIVGRELY AHGYSTGDPS KRKRGAIGSF
     ALLGLFGATV CSAFKILNWT LNPKTWC
//