Q6DCA0 (AMERL_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
AMMECR1-like protein

Gene names

Name:

AMMECR1L

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	310 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 AMMECR1 domain.

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 310	310	AMMECR1-like protein		PRO_0000278479
Regions
	Domain	97 – 291	195	AMMECR1
Amino acid modifications
	Modified residue	74	1	Phosphoserine Ref.4 Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Q6DCA0 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 6960F5A18CA02AC4	FASTA	310	34,499
	10 20 30 40 50 60 MGKRRCVPPL EPKLAAGCCG VKKPKLSGSG THSHGNQSTT VPGSSSGPLQ NHQHVDSSSG 70 80 90 100 110 120 RENVSDLTLG PGNSPITRMN PASGALSPLP RPNGTANTTK NLVVTAEMCC YCFDVLYCHL 130 140 150 160 170 180 YGFPQPRLPR FTNDPYPLFV TWKTGRDKRL RGCIGTFSAM NLHSGLREYT LTSALKDSRF 190 200 210 220 230 240 PPLTREELPK LFCSVSLLTN FEDASDYLDW EVGVHGIRIE FINEKGVKRT ATYLPEVAKE 250 260 270 280 290 300 QDWDQIQTID SLLRKGGFKA PITSEFRKTI KLTRYRSEKV TISYAEYIAS RQHCFQNGTL 310 HAPPLYNHYS

References

[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Trachea.
[2]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Colon and Testis.
[4]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed: 18669648] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-74, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[5]	"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K. Sci. Signal. 2:RA46-RA46(2009) [PubMed: 19690332] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-74, MASS SPECTROMETRY. Tissue: Leukemic T-cell.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK304145 mRNA. Translation: BAG65038.1. CH471103 Genomic DNA. Translation: EAW95346.1. BC016181 mRNA. Translation: AAH16181.1. BC078174 mRNA. Translation: AAH78174.1.
IPI	IPI00027790.
RefSeq	NP_001186069.1. NM_001199140.1. NP_113633.2. NM_031445.2.
UniGene	Hs.546449.
3D structure databases
ProteinModelPortal	Q6DCA0.
SMR	Q6DCA0. Positions 106-283.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6DCA0.
PTM databases
PhosphoSite	Q6DCA0.
Polymorphism databases
DMDM	74736367.
Proteomic databases
PRIDE	Q6DCA0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000272647; ENSP00000272647; ENSG00000144233. ENST00000393001; ENSP00000376726; ENSG00000144233.
GeneID	83607.
KEGG	hsa:83607.
UCSC	uc002tpl.1. human.
Organism-specific databases
CTD	83607.
GeneCards	GC02M128619.
H-InvDB	HIX0002444.
HGNC	HGNC:28658. AMMECR1L.
neXtProt	NX_Q6DCA0.
PharmGKB	PA162376350.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG13210.
GeneTree	ENSGT00390000010397.
HOGENOM	HBG627271.
HOVERGEN	HBG056408.
InParanoid	Q6DCA0.
OMA	RMGKRRC.
OrthoDB	EOG4VMFFH.
PhylomeDB	Q6DCA0.
Gene expression databases
ArrayExpress	Q6DCA0.
Bgee	Q6DCA0.
CleanEx	HS_AMMECR1L.
Genevestigator	Q6DCA0.
Family and domain databases
InterPro	IPR023473. AMMECR1. IPR002733. AMMECR1_domain. [Graphical view]
PANTHER	PTHR13016. PTHR13016. 1 hit.
Pfam	PF01871. AMMECR1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00296. TIGR00296. 1 hit.
PROSITE	PS51112. AMMECR1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	72559.

Entry information

Entry name

AMERL_HUMAN

Accession

Primary (citable) accession number: Q6DCA0
Secondary accession number(s): B4E276

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 20, 2007
Last sequence update:	August 16, 2004
Last modified:	January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.