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Q6DB60 (KGUA_PECAS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Guanylate kinase

EC=2.7.4.8
Alternative name(s):
GMP kinase
Gene names
Name:gmk
Ordered Locus Names:ECA0040
OrganismPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) [Complete proteome] [HAMAP]
Taxonomic identifier218491 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium

Protein attributes

Sequence length207 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP-Rule MF_00328

Catalytic activity

ATP + GMP = ADP + GDP. HAMAP-Rule MF_00328

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00328.

Sequence similarities

Belongs to the guanylate kinase family.

Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpurine nucleotide metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

guanylate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 207207Guanylate kinase HAMAP-Rule MF_00328
PRO_0000170538

Regions

Domain4 – 184181Guanylate kinase-like
Nucleotide binding11 – 188ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6DB60 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: B8D6E1D64A2E5A4C

FASTA20723,511
        10         20         30         40         50         60 
MAQGTLYIVS APSGAGKSSL IQALLKTQPL YDTQVSISHT TRAKRPGENH GEHYFFVEAD 

        70         80         90        100        110        120 
EFKRMIQDSE FLEHAEVFGN YYGTSRPAIE QVLATGVDVF LDIDWQGAQQ IRAKMPQARS 

       130        140        150        160        170        180 
IFILPPSKEE LARRLRGRGQ DSDEVIARRM SQAVAEMTHY GEYDYLIVND DFDLALLDLK 

       190        200 
TIIRAERLRL SRQKIRHDAL ITKLLAD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX950851 Genomic DNA. Translation: CAG72962.1.
RefSeqYP_048170.1. NC_004547.2.

3D structure databases

ProteinModelPortalQ6DB60.
SMRQ6DB60. Positions 2-207.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING218491.ECA0040.

Proteomic databases

PRIDEQ6DB60.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG72962; CAG72962; ECA0040.
GeneID2881491.
KEGGeca:ECA0040.
PATRIC20475231. VBIPecAtr54885_0044.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0194.
HOGENOMHOG000037638.
KOK00942.
OMAMSHYNEY.
OrthoDBEOG6CP410.

Enzyme and pathway databases

BioCycPATR218491:GJNB-43-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
HAMAPMF_00328. Guanylate_kinase.
InterProIPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTSM00072. GuKc. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR03263. guanyl_kin. 1 hit.
PROSITEPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKGUA_PECAS
AccessionPrimary (citable) accession number: Q6DB60
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: August 16, 2004
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families