Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glycerol-3-phosphate acyltransferase

Gene

plsB

Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.UniRule annotation

Pathwayi: CDP-diacylglycerol biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Glycerol-3-phosphate acyltransferase (plsB)
  2. no protein annotated in this organism
  3. Phosphatidate cytidylyltransferase (cdsA)
This subpathway is part of the pathway CDP-diacylglycerol biosynthesis, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

BioCyciPATR218491:G1G3T-653-MONOMER
UniPathwayiUPA00557; UER00612

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate acyltransferaseUniRule annotation (EC:2.3.1.15UniRule annotation)
Short name:
GPATUniRule annotation
Gene namesi
Name:plsBUniRule annotation
Ordered Locus Names:ECA0628
OrganismiPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Taxonomic identifieri218491 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaePectobacterium
Proteomesi
  • UP000007966 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000494321 – 825Glycerol-3-phosphate acyltransferaseAdd BLAST825

Proteomic databases

PRIDEiQ6D9I7

Interactioni

Protein-protein interaction databases

STRINGi218491.ECA0628

Structurei

3D structure databases

ProteinModelPortaliQ6D9I7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi306 – 311HXXXXD motif6

Domaini

The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.UniRule annotation

Sequence similaritiesi

Belongs to the GPAT/DAPAT family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105E55 Bacteria
COG2937 LUCA
HOGENOMiHOG000218231
KOiK00631
OMAiEVIYVPC
OrthoDBiPOG091H06BX

Family and domain databases

HAMAPiMF_00393 Glyc3P_acyltrans, 1 hit
InterProiView protein in InterPro
IPR022284 GPAT/DHAPAT
IPR028354 GPAT_PlsB
IPR002123 Plipid/glycerol_acylTrfase
PANTHERiPTHR12563 PTHR12563, 1 hit
PfamiView protein in Pfam
PF01553 Acyltransferase, 1 hit
PIRSFiPIRSF500064 GPAT, 1 hit
PIRSF000437 GPAT_DHAPAT, 1 hit
SMARTiView protein in SMART
SM00563 PlsC, 1 hit
TIGRFAMsiTIGR03703 plsB, 1 hit

Sequencei

Sequence statusi: Complete.

Q6D9I7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGWRKIYYK LLNLPLKLLV KSKVIPADPV VELGLDPSRP ILYVLPYNSQ
60 70 80 90 100
ADLLTLRAKC LALGLPDPSQ SFEFNGVELP SHVFINDGPR VFRYYVPKQK
110 120 130 140 150
SVKLFHDYLD LHRANPDLDV QMVPVSVMFG RSPGREGHTQ AAPHLRLLNG
160 170 180 190 200
IEKFFAVLWL GRDSFVRFSS PVSLRYMATE HGTDKTIAHK LARVARMHFS
210 220 230 240 250
RQRLAAVGPR LPVRQELFNK LLDSKAIKKA VDDEARSKKI SHEKAQQNAI
260 270 280 290 300
ALMEEIAADF SYEAVRLSDR VLSWTWNRLY QGINVHNAER VRQLAQDGHG
310 320 330 340 350
IVYVPCHRSH MDYLLLSYVL YHQGLVPPHI AAGINLNFWP AGPIFRRLGA
360 370 380 390 400
FFIRRTFKGN KLYSTIFREY LGELFARGYS VEYFMEGGRS RTGRLLDPKT
410 420 430 440 450
GTLAMTIQAM LRGGTRPITL VPIYVGYEHV MEVGTYAKEL RGAVKEKEGF
460 470 480 490 500
MQMVRGLRKL RNLGQGYVNF GEPLPLTTYL NQHVPQWRDA IDPIEAQRPS
510 520 530 540 550
WLTPTVQDIS MDIMVRINNS AAANAMNLCS TALLASRQRS LTREQMHEQL
560 570 580 590 600
DCYLQLLRQV PYHKDITAPK KTADELLEHA LGMNKFEVEK DSIGDIIILP
610 620 630 640 650
REQAVLMTYY RNNIQHLLIL PSLIASIVIH HRRITLAEVV RQITLIYPLL
660 670 680 690 700
QAELFLHYSN EQLPRVLETL ANELTRQELL CSRDGQLAIN PPRIRTLQLL
710 720 730 740 750
SAGVRETLQR YAITLSLLCA NPEINRGTLE KESRNMAQRL SVLHGINAPE
760 770 780 790 800
FFDKAVFSTL VATLRTEGYI TDSAEAAQGD IVTIYNILGD LITPEVRLTI
810 820
ESASSSTEME ASTSSSQTAE ETTQG
Length:825
Mass (Da):93,499
Last modified:August 16, 2004 - v1
Checksum:i4CD1B8F2E4FF8DFE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950851 Genomic DNA Translation: CAG73543.1
RefSeqiWP_011092246.1, NC_004547.2

Genome annotation databases

EnsemblBacteriaiCAG73543; CAG73543; ECA0628
KEGGieca:ECA0628
PATRICifig|218491.5.peg.623

Similar proteinsi

Entry informationi

Entry nameiPLSB_PECAS
AccessioniPrimary (citable) accession number: Q6D9I7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 16, 2004
Last modified: February 28, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health