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Protein

Uronate isomerase

Gene

uxaC

Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:ECA0645
OrganismiPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Taxonomic identifieri218491 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaePectobacterium
Proteomesi
  • UP000007966 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001727741 – 469Uronate isomeraseAdd BLAST469

Proteomic databases

PRIDEiQ6D9H0.

Interactioni

Protein-protein interaction databases

STRINGi218491.ECA0645.

Structurei

3D structure databases

ProteinModelPortaliQ6D9H0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6D9H0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPQFLSEDFL LDTEFARRLY HEYAVDQPIF DYHCHLPPEQ IAENYRFKNL
60 70 80 90 100
YDIWLKGDHY KWRAMRTNGV PERLCTGDAS DWEKFEAWAA TVPHTIGNPL
110 120 130 140 150
YHWTHLELRR PFGVTGTLLS PSTAKGIWDR CNAMLERDDF TARGIMQQMN
160 170 180 190 200
VKMVGTTDDP IDDLRHHKAV AQDSSFSIKV LPSWRPDKAF NIELATFNDY
210 220 230 240 250
MAKLGEVSDT DIRRFSDLQT ALTKRLDHFA AHGCKVSDHA LDVVMFAEAD
260 270 280 290 300
DATLDKILAR RLAGETLSEH EVAQFKTGVL VWLGAEYARR GWVQQYHIGA
310 320 330 340 350
LRNNNLRQFK LLGPDVGFDS INDRPLAQEL SRLLSKQNEE NLLPKTILYC
360 370 380 390 400
LNPRDNEVLG TMIGNFQGEG MPGKMQFGSG WWFNDQKDGM QRQMTQLAQL
410 420 430 440 450
GLLSRFVGML TDSRSFLSYT RHEYFRRILC QMIGRWVEDG EAPADLPLLG
460
EMVKNISFDN AKNYFAIEL
Length:469
Mass (Da):53,985
Last modified:August 16, 2004 - v1
Checksum:i489FE00FB2D75443
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950851 Genomic DNA. Translation: CAG73560.1.
RefSeqiWP_011092262.1. NC_004547.2.

Genome annotation databases

EnsemblBacteriaiCAG73560; CAG73560; ECA0645.
GeneIDi2882865.
KEGGieca:ECA0645.
PATRICi20476458. VBIPecAtr54885_0640.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950851 Genomic DNA. Translation: CAG73560.1.
RefSeqiWP_011092262.1. NC_004547.2.

3D structure databases

ProteinModelPortaliQ6D9H0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi218491.ECA0645.

Proteomic databases

PRIDEiQ6D9H0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAG73560; CAG73560; ECA0645.
GeneIDi2882865.
KEGGieca:ECA0645.
PATRICi20476458. VBIPecAtr54885_0640.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_PECAS
AccessioniPrimary (citable) accession number: Q6D9H0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: August 16, 2004
Last modified: November 2, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.