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Q6D9G9 (UXAB_PECAS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Altronate oxidoreductase

EC=1.1.1.58
Alternative name(s):
Tagaturonate dehydrogenase
Tagaturonate reductase
Gene names
Name:uxaB
Ordered Locus Names:ECA0646
OrganismPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) [Complete proteome] [HAMAP]
Taxonomic identifier218491 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium

Protein attributes

Sequence length488 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-altronate + NAD+ = D-tagaturonate + NADH. HAMAP-Rule MF_00670

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP-Rule MF_00670

Sequence similarities

Belongs to the mannitol dehydrogenase family. UxaB subfamily.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

tagaturonate reductase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 488488Altronate oxidoreductase HAMAP-Rule MF_00670
PRO_0000170744

Regions

Nucleotide binding18 – 2912NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6D9G9 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 14C477128322D778

FASTA48855,557
        10         20         30         40         50         60 
MQTLNRRNFP GRQHPDRVIQ FGEGNFLRAF VDWQLDLLNE HTDLDAGIVI VRPIDSDFPP 

        70         80         90        100        110        120 
ALDTQDGLYT TIIRGLNEQG EAVREPRLIR SVNREINVYR QFDEYLALAH DPNIRFVFSN 

       130        140        150        160        170        180 
TTEAGISYHA DDRLSDAPPV SFPAKLTRLL YERFCHFDGA ADKGWVLLPC ELIDYNGVAL 

       190        200        210        220        230        240 
KELVLRYAAQ WELTSTFTAW LNDHNTFCST LVDRIVTGYP RAEVEALQQE MGYQDTFWDT 

       250        260        270        280        290        300 
AEHFYLFVIQ GPLWLAEELR LNKLDLNVRI VDDIKPYKER KVAILNGAHT ALVPVAFLAG 

       310        320        330        340        350        360 
LDTVGESMND ALIGKFVEKT IAEEIVPVLD LPHDELTSFA QAVLSRFRNP FIQHQLLSIS 

       370        380        390        400        410        420 
LNGMTKFRTR ILPQLLTYRE RHGELPARLT FALAALIAFY RGERSGEGDA LQAYPLQDDA 

       430        440        450        460        470        480 
HWLERYSTLW AGVKENTVSL AELVNVVLRD ADHWEQDLTQ VPGLAAQVTE QLQTIVERGM 


RAAVEGYC 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX950851 Genomic DNA. Translation: CAG73561.1.
RefSeqYP_048762.1. NC_004547.2.

3D structure databases

ProteinModelPortalQ6D9G9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING218491.ECA0646.

Proteomic databases

PRIDEQ6D9G9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG73561; CAG73561; ECA0646.
GeneID2882732.
KEGGeca:ECA0646.
PATRIC20476460. VBIPecAtr54885_0641.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0246.
HOGENOMHOG000029586.
KOK00041.
OMAHNTFCST.
OrthoDBEOG6CVVB8.

Enzyme and pathway databases

BioCycPATR218491:GJNB-662-MONOMER.
UniPathwayUPA00246.

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPMF_00670. Altron_oxidoreduct.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
SUPFAMSSF48179. SSF48179. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUXAB_PECAS
AccessionPrimary (citable) accession number: Q6D9G9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: August 16, 2004
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways