Q6D984 (RSMC_ERWCT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase C
EC=2.1.1.172

Alternative name(s):
16S rRNA m2G1207 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RsmC

Gene names

Name:	rsmC
Ordered Locus Names:	ECA0735

Organism

Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) [Complete proteome] [HAMAP]

Taxonomic identifier

29471 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pectobacterium

Protein attributes

Sequence length	348 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle By similarity. HAMAP MF_01862
Catalytic activity	S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1207) in 16S rRNA. HAMAP MF_01862
Subunit structure	Monomer By similarity. HAMAP MF_01862
Subcellular location	Cytoplasm Potential HAMAP MF_01862.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmC family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 348	348	Ribosomal RNA small subunit methyltransferase C HAMAP MF_01862		PRO_0000369696

Sequences

	Sequence		Length	Mass (Da)
	Q6D984 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 85A6ACB7FF35D386	FASTA	348	37,926
	10 20 30 40 50 60 MSALTPASEV ILRHSDEFLS RRVLFAGDLQ DTLPAQFEAA SVRVHCNQYH HWQQMAKPLG 70 80 90 100 110 120 DNAQYSLVAD AELVADSDTL IYYWPKSKQE AEFQLCNLLS LLPVGAEIFV VGENRSGVRS 130 140 150 160 170 180 AETVLSDFVE LVKIDSARRC GLYHGRIDKQ ASFTLDDWWD EYVTEGVTVK TLPGIFSRDG 190 200 210 220 230 240 LDPGSRLLLS TFEPHMKGKV LDIACGAGVL ASVLAKQSPK IRLTLSDVSA AAVESSNATL 250 260 270 280 290 300 AANALEGSVI ASNVYSDIDG RFDMIVSNPP FHDGLQTSLQ AVEMLIRGAV THLPIGGQLR 310 320 330 340 IVANAFLPYP ALLDAAFGSH EVLAQTGRFK VYQATVGRPP RTGKGRRR

References

[1]

"Genome sequence of the enterobacterial phytopathogen Erwinia carotovora subsp. atroseptica and characterization of virulence factors." Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J., Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K., Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J., Fraser A., Hance Z. , Hauser H., Jagels K., Moule S., Norbertczak H., Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S., Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K. Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004) [PubMed: 15263089] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SCRI 1043 / ATCC BAA-672.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX950851 Genomic DNA. Translation: CAG73649.1.
RefSeq	YP_048847.1. NC_004547.2.
3D structure databases
ProteinModelPortal	Q6D984.
SMR	Q6D984. Positions 3-334.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2884450.
GenomeReviews	Gene locus ECA0735 in contig BX950851_GR.
KEGG	eca:ECA0735.
NMPDR	fig|218491.3.peg.3304.
PATRIC	20476650. VBIPecAtr54885_0733.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG296757.
OMA	TGKFKVY.
ProtClustDB	PRK09489.
Enzyme and pathway databases
BioCyc	ECAR218491:ECA0735-MONOMER.
Family and domain databases
HAMAP	MF_01862. 16SrRNA_methyltr_C. [Tree]
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. IPR013675. Mtase_sm_N. IPR023543. rRNA_ssu_MeTfrase_C. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. PF08468. MTS_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RSMC_ERWCT

Accession

Primary (citable) accession number: Q6D984

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	August 16, 2004
Last modified:	January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program