Reviewed, UniProtKB/Swiss-Prot Q6D8W0 (TAL1_ERWCT)

Names and origin

Protein names

Recommended name:
    Transaldolase 1
    EC=2.2.1.2

Gene names

Name:	tal1
Ordered Locus Names:	ECA0862

Organism

Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) [Complete proteome] [HAMAP]

Taxonomic identifier

29471 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pectobacterium

Protein attributes

Sequence length	316 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00492
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00492
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00492
Subcellular location	Cytoplasm Probable HAMAP MF_00492.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transaldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 316	316	Transaldolase 1 HAMAP MF_00492		PRO_0000230952
Sites
	Active site	131	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6D8W0-1 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 328F65E858CC6324	FASTA	316	35,179
	10 20 30 40 50 60 MNQLEALKQF TVVVADSGDI DSIRQFSPQD ATTNPSLILK AATLPQYQPL FDDAIAYANL 70 80 90 100 110 120 QGGSPETRLI NASDRLAVNI GAEVLKSIPG RISTEVDARL SFDRGMCVAK ARKLIGMYQE 130 140 150 160 170 180 KDIPRSRILI KLAATWEGIR AAEELEKEGI NCNLTLLFSF AQARACAEAG VFLISPFVGR 190 200 210 220 230 240 IYDWYQEKQP TSDYQAESDP GVISVRDIYD YYKRHRYQTV IMGASFRKVE QILALAGCDR 250 260 270 280 290 300 LTISPALLEQ LKNSSDPVER QLTPSTEAFH PPSPLSEAEF RWEHHQDAMA VDKLAEGIRL 310 FAADQQKLEA LLAAKL

References

[1]

"Genome sequence of the enterobacterial phytopathogen Erwinia carotovora subsp. atroseptica and characterization of virulence factors." Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J., Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K., Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J., Fraser A., Hance Z. , Hauser H., Jagels K., Moule S., Norbertczak H., Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S., Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K. Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004) [PubMed: 15263089] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SCRI 1043 / ATCC BAA-672.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX950851 Genomic DNA. Translation: CAG73774.1.
RefSeq	YP_048971.1.
3D structure databases
SMR	Q6D8W0. Positions 2-313.
ModBase	Search...
Genome annotation databases
GeneID	2884325.
GenomeReviews	Gene locus ECA0862 in contig BX950851_GR.
KEGG	eca:ECA0862.
NMPDR	fig|218491.3.peg.3707.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG286747.
OMA	FDTSATV.
Enzyme and pathway databases
BioCyc	ECAR218491:ECA0862-MONOMER.
BRENDA	2.2.1.2. 281579.
Family and domain databases
HAMAP	MF_00492. Transaldolase_1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_AB. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10683. Transaldolase. 1 hit. PTHR10683:SF3. Transaldolase_AB. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. talAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL1_ERWCT

Accession

Primary (citable) accession number: Q6D8W0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	August 16, 2004
Last modified:	February 9, 2010
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)