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Q6D7J7 (SYQ_PECAS) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:ECA1328
OrganismPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) [Complete proteome] [HAMAP]
Taxonomic identifier218491 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium

Protein attributes

Sequence length552 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 552552Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_0000242869

Regions

Motif34 – 4411"HIGH" region HAMAP-Rule MF_00126
Motif268 – 2725"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site2711ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6D7J7 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 57828D6FD0034782

FASTA55263,182
        10         20         30         40         50         60 
MSEAEARPTN FIRQIIDEDL ASGKHDHIQT RFPPEPNGYL HIGHAKSICL NFGIARDYQG 

        70         80         90        100        110        120 
QCNLRFDDTN PVKEDIEYVE SIKRDVEWLG FSWSGDVRYS SDYFDQLHAY AVELIGKGLA 

       130        140        150        160        170        180 
YVDELTPEQI REYRGTLTAP GKNSPYRDRT VQENLALFEK MRNGGFAEGT ACLRAKIDMA 

       190        200        210        220        230        240 
SSFIVMRDPV LYRIKFADHH QTGNKWCIYP MYDFTHCISD ALEGITHSLC TLEFQDNRRL 

       250        260        270        280        290        300 
YDWVLDNISI PCHPRQYEFS RLNLEYAIMS KRKLNQLVVE NVVEGWDDPR MPTISGLRRR 

       310        320        330        340        350        360 
GYSASSIREF CVRIGVTKQD NNVEMAALES CIRDDLNENA PRAMAVLDPV KVVIENLPAG 

       370        380        390        400        410        420 
HEEFVAMPNH PNKPEMGSRQ VAFSREVYID RADFREEANK QYKRLVLGKE VRLRNAYVIK 

       430        440        450        460        470        480 
ADRIEKDEQG TITTIYCSYD AETLSKDPAD GRKVKGVIHW VSAAHAVPAE FRLYDRLFSV 

       490        500        510        520        530        540 
ANPAAADDFL STINPDSLKI TQGFVEASLV QAEVEKAYQF EREGYFCADR VYSSAEHLVF 

       550 
NRTVGLRDTW VG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX950851 Genomic DNA. Translation: CAG74238.1.
RefSeqYP_049434.1. NC_004547.2.

3D structure databases

ProteinModelPortalQ6D7J7.
SMRQ6D7J7. Positions 9-549.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING218491.ECA1328.

Proteomic databases

PRIDEQ6D7J7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG74238; CAG74238; ECA1328.
GeneID2881330.
KEGGeca:ECA1328.
PATRIC20477924. VBIPecAtr54885_1357.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259232.
KOK01886.
OMAVTHSICT.
OrthoDBEOG6DRPF7.
ProtClustDBPRK05347.

Enzyme and pathway databases

BioCycPATR218491:GJNB-1365-MONOMER.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_PECAS
AccessionPrimary (citable) accession number: Q6D7J7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: August 16, 2004
Last modified: April 16, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries