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Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.UniRule annotation

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glucose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Enzyme and pathway databases

BioCyciPATR218491:GJNB-1443-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonaseUniRule annotation (EC:3.1.1.31UniRule annotation)
Short name:
6-P-gluconolactonaseUniRule annotation
Gene namesi
Name:pglUniRule annotation
Ordered Locus Names:ECA1403
OrganismiPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Taxonomic identifieri218491 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium
ProteomesiUP000007966: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3323326-phosphogluconolactonasePRO_0000171135Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi218491.ECA1403.

Structurei

3D structure databases

ProteinModelPortaliQ6D7C2.
SMRiQ6D7C2. Positions 1-330.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cycloisomerase 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2706.
HOGENOMiHOG000257418.
KOiK07404.
OMAiGHQPTET.
OrthoDBiEOG615VK7.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_01605. 6P_gluconolactonase.
InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF10282. Lactonase. 1 hit.
[Graphical view]
SUPFAMiSSF50974. SSF50974. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6D7C2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQVVYVASP ESQQIHVWQL GAQGNLTLLQ TVEVPGQVQP MAIAPNKRHL
60 70 80 90 100
YVGVRPDFRV LSYRIDEQGK LTEAGVASLP GSPTHLSTDN DGRFLFSASY
110 120 130 140 150
SGACVSVSPI DADGIVGEPI QQLDGLEGCH STNIDPTNTV VWAPCLKEDR
160 170 180 190 200
IRLYDLGSVG ELSIHRQAEM TTVSGAGPRH MAFHPNQRFA YCVNELDSSV
210 220 230 240 250
DVYQLDAASG DVQKVQTLDA MPAGFSDTRW AADIHITPNG NFLYISDRTA
260 270 280 290 300
SLLSVFQISE DGSTLTLTGH QPTETQPRGF NIDHTGEFLI SAGQKSQHIE
310 320 330
VYHIDQHTGD LQPLARYAVG QGPMWVAVLA LD
Length:332
Mass (Da):36,134
Last modified:August 16, 2004 - v1
Checksum:iF2EEB874B1D0CE65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950851 Genomic DNA. Translation: CAG74313.1.
RefSeqiYP_049509.1. NC_004547.2.

Genome annotation databases

EnsemblBacteriaiCAG74313; CAG74313; ECA1403.
GeneIDi2884854.
KEGGieca:ECA1403.
PATRICi20478094. VBIPecAtr54885_1439.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950851 Genomic DNA. Translation: CAG74313.1.
RefSeqiYP_049509.1. NC_004547.2.

3D structure databases

ProteinModelPortaliQ6D7C2.
SMRiQ6D7C2. Positions 1-330.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi218491.ECA1403.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAG74313; CAG74313; ECA1403.
GeneIDi2884854.
KEGGieca:ECA1403.
PATRICi20478094. VBIPecAtr54885_1439.

Phylogenomic databases

eggNOGiCOG2706.
HOGENOMiHOG000257418.
KOiK07404.
OMAiGHQPTET.
OrthoDBiEOG615VK7.

Enzyme and pathway databases

UniPathwayiUPA00115; UER00409.
BioCyciPATR218491:GJNB-1443-MONOMER.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_01605. 6P_gluconolactonase.
InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF10282. Lactonase. 1 hit.
[Graphical view]
SUPFAMiSSF50974. SSF50974. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SCRI 1043 / ATCC BAA-672.

Entry informationi

Entry namei6PGL_PECAS
AccessioniPrimary (citable) accession number: Q6D7C2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: August 16, 2004
Last modified: March 4, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.