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Protein

Ribosomal RNA small subunit methyltransferase F

Gene

rsmF

Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(1407) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(1407) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei150S-adenosyl-L-methionineUniRule annotation1
Binding sitei177S-adenosyl-L-methionineUniRule annotation1
Binding sitei195S-adenosyl-L-methionineUniRule annotation1
Active sitei248NucleophileUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, RNA-binding, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPATR218491:G1G3T-2514-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase FUniRule annotation (EC:2.1.1.178UniRule annotation)
Alternative name(s):
16S rRNA m5C1407 methyltransferaseUniRule annotation
rRNA (cytosine-C(5)-)-methyltransferase RsmFUniRule annotation
Gene namesi
Name:rsmFUniRule annotation
Ordered Locus Names:ECA2464
OrganismiPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Taxonomic identifieri218491 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaePectobacterium
Proteomesi
  • UP000007966 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002849961 – 484Ribosomal RNA small subunit methyltransferase FAdd BLAST484

Interactioni

Protein-protein interaction databases

STRINGi218491.ECA2464

Structurei

3D structure databases

ProteinModelPortaliQ6D4C8
SMRiQ6D4C8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni126 – 132S-adenosyl-L-methionine bindingUniRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CYJ Bacteria
COG0144 LUCA
COG3270 LUCA
HOGENOMiHOG000218115
KOiK11392
OMAiDPLFHAG
OrthoDBiPOG091H02E2

Family and domain databases

HAMAPiMF_01579 16SrRNA_methyltr_F, 1 hit
InterProiView protein in InterPro
IPR018314 Fmu/NOL1/Nop2p_CS
IPR031341 Methyltr_RsmF_N
IPR001678 MeTrfase_RsmB/NOP2
IPR027391 Nol1_Nop2_Fmu_2
IPR011023 Nop2p
IPR023267 RCMT
IPR023545 rRNA_ssu_MeTfrase_F
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF17125 Methyltr_RsmF_N, 1 hit
PF13636 Methyltranf_PUA, 1 hit
PRINTSiPR02008 RCMTFAMILY
SUPFAMiSSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00446 nop2p, 1 hit
PROSITEiView protein in PROSITE
PS01153 NOL1_NOP2_SUN, 1 hit
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

Q6D4C8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKFTPASLP AEFLDTMRDI MPSSLSMEDF IAACQRPLRR SIRVNTLKIS
60 70 80 90 100
VDAFLQLAQP YGWQLEPIPW CQEGFWLLNA EEENTRLGNT LEHLSGLFYI
110 120 130 140 150
QEASSMLPAS ALFHHNDAPG TILDVAAAPG SKTTQIAARL NNEGAIVANE
160 170 180 190 200
YSASRVKVLH ANISRCGVSN TAITHFDGRV FGAALPEYFD AILLDAPCSG
210 220 230 240 250
EGVVRKDPAA MSHWSQESIT DIAATQRDLI LSAFHALKPG GVMIYSTCTL
260 270 280 290 300
NRQENQQVCR WLQAQFPDAC EFESLDDLFA GAERATTEEG FLHVFPQIYD
310 320 330 340 350
SEGFFVARLR KTGSVPPLPR PGYKVGKFPF SPVAHKDRAL LTEAARKQGI
360 370 380 390 400
RWDEELLQLW QRDSEVWLFP AALTSAFGNI KFSRIGIKLA ERFPKGFRWQ
410 420 430 440 450
HEAIVALADP NASNAYALND RIACEWFQGK DSYPEPLPTA DELILTYQNT
460 470 480
PVGLAKRISS RIKNSLPRDL VRDGASSARP LAKE
Length:484
Mass (Da):53,741
Last modified:August 16, 2004 - v1
Checksum:i76E7DE97E08DA2BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950851 Genomic DNA Translation: CAG75365.1
RefSeqiWP_011094014.1, NC_004547.2

Genome annotation databases

EnsemblBacteriaiCAG75365; CAG75365; ECA2464
KEGGieca:ECA2464
PATRICifig|218491.5.peg.2493

Similar proteinsi

Entry informationi

Entry nameiRSMF_PECAS
AccessioniPrimary (citable) accession number: Q6D4C8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: August 16, 2004
Last modified: February 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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