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Q6D454 (PNCB_PECAS) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:ECA2540
OrganismPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) [Complete proteome] [HAMAP]
Taxonomic identifier218491 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205831

Sequences

Sequence LengthMass (Da)Tools
Q6D454 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: B9241D05BE30246F

FASTA40145,867
        10         20         30         40         50         60 
MTLHTSPILH SLLDTDAYKL HMQQAVYHHY YDVDVAAEFR CRGDELLGVY ADEIAHQVDL 

        70         80         90        100        110        120 
MRFLSLSDDE FTYLSSLPFF QQDYLNWLRN FRFNPQQVSI KNNAGKLDIR ITGPWREVIL 

       130        140        150        160        170        180 
WEVPLLAVIS EVVHRHRSPN VTTEQAVAQL STSLESFRQN SMNVDLSQFK LMDFGTRRRF 

       190        200        210        220        230        240 
SGDIQQTIVT ALQADFPYLI GTSNYDLARR LGITPVGTQA HEWFQAHQQI SPTLANSQRA 

       250        260        270        280        290        300 
ALQMWLREYP THLGIALTDC ITMDAFLRDF DLPFAEAYQG LRHDSGDPVD WGEKAIAHYQ 

       310        320        330        340        350        360 
RLNIDPMSKT LVFSDNLNLD KALVLYRHFC QRVNLVFGMG TRLTCDIPGV KPLNIVIKLV 

       370        380        390        400 
ECNGKPVAKL SDSPGKTICQ DQNFVCELRK AFDLPRVKKA S 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX950851 Genomic DNA. Translation: CAG75439.1.
RefSeqYP_050631.1. NC_004547.2.

3D structure databases

ProteinModelPortalQ6D454.
SMRQ6D454. Positions 3-378.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING218491.ECA2540.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG75439; CAG75439; ECA2540.
GeneID2883276.
KEGGeca:ECA2540.
PATRIC20480377. VBIPecAtr54885_2572.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycPATR218491:GJNB-2583-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_PECAS
AccessionPrimary (citable) accession number: Q6D454
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: August 16, 2004
Last modified: April 16, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways