Reviewed, UniProtKB/Swiss-Prot Q6D2L3 (MQO_ERWCT)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	ECA3082

Organism

Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) [Complete proteome] [HAMAP]

Taxonomic identifier

29471 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pectobacterium

Protein attributes

Sequence length	527 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor.
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 527	527	Probable malate:quinone oxidoreductase		PRO_1000023800

Sequences

	Sequence		Length	Mass (Da)
	Q6D2L3-1 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 35D674A15C000ACD	FASTA	527	58,123
	10 20 30 40 50 60 MKKLLAMFFC LSVVVSAPLA MAEDAKTTEK TTDVVLIGGG IMSSTLGVYL QELQPDWSID 70 80 90 100 110 120 MVERMDNVAE ESSNGWNNAG TGHSAFMELN YTPDNPDGPI NISKALEITE AFEISRQFWS 130 140 150 160 170 180 YQVKNGVLNN PHAFINSVPH ISFVWGDENT AFLKHRYDAM QHSTLYRGME FSDDPNTIKE 190 200 210 220 230 240 WVPLVMEGRD PAQKIAATRM PIGTDVNYGE ITRQLVSAMK TKSNFALHLN SEVRDIKRNA 250 260 270 280 290 300 DNTWSVTYAD LKNGEKESVI KAKFVFIGAG GAALKLLQKS GIPEADLYGG FPVGGEFLVT 310 320 330 340 350 360 ENPEIVKRHM AKVYGKASVG APPMSVPHLD TRIFDGKPVL LFGPFATFSS KFLKNGSLWD 370 380 390 400 410 420 LIGSVTFSNV MPMTHVGLDN FDLVKYLVSQ VMMDDDDRFA SLQEYFPNAK KEDWRLTVAG 430 440 450 460 470 480 QRVQVIKKDD DKGGVLKLGT EIVSSQDGSI AALLGASPGA STAAPIMLSL LEKVFKDKVA 490 500 510 520 TPEWQSKLKE IVPSYGQKLD GNIEMTNKIR SYTSSTLGLD YIEVKPE

References

[1]

"Genome sequence of the enterobacterial phytopathogen Erwinia carotovora subsp. atroseptica and characterization of virulence factors." Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J., Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K., Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J., Fraser A., Hance Z. , Hauser H., Jagels K., Moule S., Norbertczak H., Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S., Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K. Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004) [PubMed: 15263089] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SCRI 1043 / ATCC BAA-672.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX950851 Genomic DNA. Translation: CAG75981.1.
RefSeq	YP_051172.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2881697.
GenomeReviews	Gene locus ECA3082 in contig BX950851_GR.
KEGG	eca:ECA3082.
NMPDR	fig|218491.3.peg.1438.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6D2L3.
Enzyme and pathway databases
BioCyc	ECAR218491:ECA3082-MON.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_ERWCT

Accession

Primary (citable) accession number: Q6D2L3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 16, 2004
Last modified:	November 4, 2008
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)