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Q6D2F2 (ARND_PECAS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD

EC=3.5.1.n3
Gene names
Name:arnD
Ordered Locus Names:ECA3143
OrganismPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) [Complete proteome] [HAMAP]
Taxonomic identifier218491 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides By similarity. HAMAP-Rule MF_01870

Catalytic activity

4-deoxy-4-formamido-beta-L-arabinose di-trans,poly-cis-undecaprenyl phosphate + H2O = 4-amino-4-deoxy-alpha-L-arabinose di-trans,poly-cis-undecaprenyl phosphate + formate. HAMAP-Rule MF_01870

Pathway

Glycolipid biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate from UDP-4-deoxy-4-formamido-beta-L-arabinose and undecaprenyl phosphate: step 2/2. HAMAP-Rule MF_01870

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP-Rule MF_01870

Sequence similarities

Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.

Contains 1 NodB homology domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 297297Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD HAMAP-Rule MF_01870
PRO_0000383493

Regions

Domain2 – 261260NodB homology

Sequences

Sequence LengthMass (Da)Tools
Q6D2F2 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 83F59EC57E0954AA

FASTA29733,439
        10         20         30         40         50         60 
MTRVGLRIDV DTWRGTRDGV PALLKVLAEF DIQASFFFSV GPDNMGRHLW RLLRPRFLWK 

        70         80         90        100        110        120 
MLRSNAASLY GWDILLAGTA WPGRHIGARF GSLIRQTHDA GHEVGLHSWD HHGWQANVAR 

       130        140        150        160        170        180 
WSDAQLAAQF HEGMDALTQI LPSPVRCSAV AGWRADARVV EMKQRWNLDY NSDCRGTQPF 

       190        200        210        220        230        240 
RPRLKNGGLG TTQIPVTLPT YDEVIGERVS DGEFNDFILD AIEQDRGVPV YTIHAEVEGG 

       250        260        270        280        290 
AKLALFRQLL LLARQRHIEF CPLSSLLPDD STTLPVGRIE RAPFPGREGW LGVQTEE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX950851 Genomic DNA. Translation: CAG76042.1.
RefSeqYP_051233.1. NC_004547.2.

3D structure databases

ProteinModelPortalQ6D2F2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING218491.ECA3143.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG76042; CAG76042; ECA3143.
GeneID2882942.
KEGGeca:ECA3143.
PATRIC20481609. VBIPecAtr54885_3180.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0726.
HOGENOMHOG000261199.
KOK13014.
OMALHAWDHF.
OrthoDBEOG6423D0.

Enzyme and pathway databases

BioCycPATR218491:GJNB-3193-MONOMER.
UniPathwayUPA00030.
UPA00036; UER00496.

Family and domain databases

Gene3D3.20.20.370. 2 hits.
HAMAPMF_01870. ArnD.
InterProIPR023557. ArnD.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR002509. Polysac_deacetylase.
[Graphical view]
PfamPF01522. Polysacc_deac_1. 1 hit.
[Graphical view]
SUPFAMSSF88713. SSF88713. 2 hits.
PROSITEPS51677. NODB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARND_PECAS
AccessionPrimary (citable) accession number: Q6D2F2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: August 16, 2004
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways