Reviewed, UniProtKB/Swiss-Prot Q6CZL2 (GLPE_ERWCT)

Names and origin

Protein names

Recommended name:
    Thiosulfate sulfurtransferase glpE
    EC=2.8.1.1

Gene names

Name:	glpE
Ordered Locus Names:	ECA4139

Organism

Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) [Complete proteome] [HAMAP]

Taxonomic identifier

29471 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pectobacterium

Protein attributes

Sequence length	105 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide By similarity. HAMAP MF_01009
Catalytic activity	Thiosulfate + cyanide = sulfite + thiocyanate. HAMAP MF_01009
Subcellular location	Cytoplasm By similarity HAMAP MF_01009.
Sequence similarities	Belongs to the glpE family. Contains 1 rhodanese domain.

Ontologies

Keywords
Biological process	Glycerol metabolism
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycerol metabolic process Inferred from electronic annotation. Source: HAMAP sulfate transport Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	thiosulfate sulfurtransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 105	105	Thiosulfate sulfurtransferase glpE HAMAP MF_01009		PRO_0000200551
Regions
	Domain	16 – 104	89	Rhodanese
Sites
	Active site	64	1	Cysteine persulfide intermediate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6CZL2-1 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 0EB26357B62F9178	FASTA	105	11,670
	10 20 30 40 50 60 MEQFEAISIE QAHSRWQEGG VVVDIRDPQS FAAAHVPGAT HLTNETLPDF VRGADFEAPV 70 80 90 100 MVICYHGISS RNAAQYLISQ GFDSVYSIDG GFEAWQHRYP QDTQA

References

[1]

"Genome sequence of the enterobacterial phytopathogen Erwinia carotovora subsp. atroseptica and characterization of virulence factors." Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J., Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K., Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J., Fraser A., Hance Z. , Hauser H., Jagels K., Moule S., Norbertczak H., Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S., Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K. Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004) [PubMed: 15263089] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SCRI 1043 / ATCC BAA-672.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX950851 Genomic DNA. Translation: CAG77036.1.
RefSeq	YP_052226.1.
3D structure databases
SMR	Q6CZL2. Positions 1-102.
ModBase	Search...
Genome annotation databases
GeneID	2881264.
GenomeReviews	Gene locus ECA4139 in contig BX950851_GR.
KEGG	eca:ECA4139.
NMPDR	fig|218491.3.peg.2158.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG743107.
OMA	AWHRHFP.
Enzyme and pathway databases
BioCyc	ECAR218491:ECA4139-MONOMER.
BRENDA	2.8.1.1. 281579.
Family and domain databases
HAMAP	MF_01009. Thiosulf_sulfurtr. [Tree]
InterPro	IPR001763. Rhodanese-like. IPR001307. Thiosulphate_STrfase_CS. [Graphical view]
Gene3D	G3DSA:3.40.250.10. Rhodanese-like. 1 hit.
Pfam	PF00581. Rhodanese. 1 hit. [Graphical view]
SMART	SM00450. RHOD. 1 hit. [Graphical view]
PROSITE	PS00380. RHODANESE_1. 1 hit. PS50206. RHODANESE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLPE_ERWCT

Accession

Primary (citable) accession number: Q6CZL2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 2005
Last sequence update:	August 16, 2004
Last modified:	January 19, 2010
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)