Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6CZD8

- GPPA_PECAS

UniProt

Q6CZD8 - GPPA_PECAS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase

Gene

gppA

Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the "stringent response", an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.UniRule annotation

Catalytic activityi

Guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 3',5'-bis(diphosphate) + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. exopolyphosphatase activity Source: InterPro
  2. guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity Source: UniProtKB-EC
  3. magnesium ion binding Source: InterPro

GO - Biological processi

  1. guanosine pentaphosphate catabolic process Source: InterPro
  2. guanosine tetraphosphate biosynthetic process Source: UniProtKB-UniPathway
  3. polyphosphate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciPATR218491:GJNB-4303-MONOMER.
UniPathwayiUPA00908; UER00884.

Names & Taxonomyi

Protein namesi
Recommended name:
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphataseUniRule annotation (EC:3.6.1.40UniRule annotation)
Alternative name(s):
Guanosine pentaphosphate phosphohydrolaseUniRule annotation
pppGpp-5'-phosphohydrolaseUniRule annotation
Gene namesi
Name:gppAUniRule annotation
Ordered Locus Names:ECA4214
OrganismiPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Taxonomic identifieri218491 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium
ProteomesiUP000007966: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 498498Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatasePRO_0000194279Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi218491.ECA4214.

Structurei

3D structure databases

ProteinModelPortaliQ6CZD8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GppA/Ppx family. GppA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0248.
HOGENOMiHOG000258672.
KOiK01524.
OMAiGLHIEYK.
OrthoDBiEOG6M6JN6.

Family and domain databases

HAMAPiMF_01550. GppA.
InterProiIPR022371. Exopolyphosphatase.
IPR023709. Guo-5TP_3DP_PyrP.
IPR003695. Ppx_GppA.
[Graphical view]
PfamiPF02541. Ppx-GppA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03706. exo_poly_only. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6CZD8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLSSSSLYAA IDLGSNSFHM LVTRETAGSI QTLAKIKRKV RLAAGLDKQN
60 70 80 90 100
RLSQEAMQRG WQCLQLFSER LQDIPQDQVR VVATATLRLA TNADEFLQRA
110 120 130 140 150
QEILGLPIQV ISGEEEARLI YQGVAHTTGG PDARLVVDIG GGSTELATGI
160 170 180 190 200
GAKTTQLISL PMGCVTWLDR YFSDRNLEAG NFERAENAAR EMLRPVAASL
210 220 230 240 250
REQGWQICVG ASGTVQALQE IMVAQGMDEY ITLPKLRQLK EHAIQCDKLE
260 270 280 290 300
ELEIDGLTLE RALVFPSGLA ILLAIFQELD IKTMTLAGGA LREGLVYGML
310 320 330 340 350
HLPVDQDIRH RTLATLQRRY LLDTEQAKRV STLADNFLQQ VARDWQLDSR
360 370 380 390 400
CRELLRSACM VHEIGLSIDF RQSPQHAAYL IRHSDLPGFT PAQKKLLATL
410 420 430 440 450
LQNQINPIDL MPLSQQNALP VNQAQHLCRL LRLAIIFASR RRDDTLPAVR
460 470 480 490
LRVEGEALRL ILPAGWLAQH PLRAEMLEQE SRWQSYVHWP LMLEEAPA
Length:498
Mass (Da):55,719
Last modified:August 16, 2004 - v1
Checksum:i7AC67D354A932836
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950851 Genomic DNA. Translation: CAG77111.1.
RefSeqiYP_052301.1. NC_004547.2.

Genome annotation databases

EnsemblBacteriaiCAG77111; CAG77111; ECA4214.
GeneIDi2885504.
KEGGieca:ECA4214.
PATRICi20483897. VBIPecAtr54885_4290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950851 Genomic DNA. Translation: CAG77111.1 .
RefSeqi YP_052301.1. NC_004547.2.

3D structure databases

ProteinModelPortali Q6CZD8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 218491.ECA4214.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAG77111 ; CAG77111 ; ECA4214 .
GeneIDi 2885504.
KEGGi eca:ECA4214.
PATRICi 20483897. VBIPecAtr54885_4290.

Phylogenomic databases

eggNOGi COG0248.
HOGENOMi HOG000258672.
KOi K01524.
OMAi GLHIEYK.
OrthoDBi EOG6M6JN6.

Enzyme and pathway databases

UniPathwayi UPA00908 ; UER00884 .
BioCyci PATR218491:GJNB-4303-MONOMER.

Family and domain databases

HAMAPi MF_01550. GppA.
InterProi IPR022371. Exopolyphosphatase.
IPR023709. Guo-5TP_3DP_PyrP.
IPR003695. Ppx_GppA.
[Graphical view ]
Pfami PF02541. Ppx-GppA. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR03706. exo_poly_only. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SCRI 1043 / ATCC BAA-672.

Entry informationi

Entry nameiGPPA_PECAS
AccessioniPrimary (citable) accession number: Q6CZD8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: August 16, 2004
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3