Q6CZB6 (MURI_ERWCT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	ECA4237

Organism

Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) [Complete proteome] [HAMAP]

Taxonomic identifier

29471 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pectobacterium

Protein attributes

Sequence length	285 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 285	285	Glutamate racemase HAMAP MF_00258		PRO_1000047565

Sequences

	Sequence		Length	Mass (Da)
	Q6CZB6 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 0FAD25A59E437DFC	FASTA	285	31,405
	10 20 30 40 50 60 MATARQGENT ISLEAIPSNL PSRPTILVFD SGVGGLSVYD EIRQLLPDLH YIYAFDNEAF 70 80 90 100 110 120 PYGEKSQQFI IERVVEIVSA VQQRHQLALV VIACNTASTI SLPALRERFT FPVVGVVPAV 130 140 150 160 170 180 KPAAKLTRNG VVGLLATRAT VQRPYTHELI TRFATDCQIL SLGSSELVEL AEAKLQGEAI 190 200 210 220 230 240 SISELQKILR PWLRLTEPPD TVVLGCTHFP LLAEELKMVL PEGTRLVDSG AAIAKRTAWL 250 260 270 280 IANLDNPPLS TDRNLVYCLK ITPKVATLWP ILQRYGFNSL EKLPL

References

[1]

"Genome sequence of the enterobacterial phytopathogen Erwinia carotovora subsp. atroseptica and characterization of virulence factors." Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J., Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K., Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J., Fraser A., Hance Z. , Hauser H., Jagels K., Moule S., Norbertczak H., Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S., Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K. Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004) [PubMed: 15263089] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SCRI 1043 / ATCC BAA-672.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX950851 Genomic DNA. Translation: CAG77134.1.
RefSeq	YP_052324.1. NC_004547.2.
3D structure databases
HSSP	HSSP built from PDB template 1B74 based on UniProtKB P56868.
ProteinModelPortal	Q6CZB6.
SMR	Q6CZB6. Positions 23-283.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2882085.
GenomeReviews	Gene locus ECA4237 in contig BX950851_GR.
KEGG	eca:ECA4237.
NMPDR	fig|218491.3.peg.482.
PATRIC	20483957. VBIPecAtr54885_4314.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG645102.
OMA	PQEDTIY.
ProtClustDB	PRK00865.
Enzyme and pathway databases
BioCyc	ECAR218491:ECA4237-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_ERWCT

Accession

Primary (citable) accession number: Q6CZB6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 16, 2004
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program