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Protein

Small heat shock protein IbpB

Gene

ibpB

Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Small heat shock protein IbpBUniRule annotation
Alternative name(s):
16 kDa heat shock protein BUniRule annotation
Gene namesi
Name:ibpBUniRule annotation
Ordered Locus Names:ECA4402
OrganismiPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Taxonomic identifieri218491 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaePectobacterium
Proteomesi
  • UP000007966 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001260311 – 150Small heat shock protein IbpBAdd BLAST150

Proteomic databases

PRIDEiQ6CYV3.

Interactioni

Subunit structurei

Homodimer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to oligomers at high temperatures or high ionic concentrations. The decrease in size of the multimers is accompanied by an increase in chaperone activity.UniRule annotation

Protein-protein interaction databases

STRINGi218491.ECA4402.

Structurei

3D structure databases

ProteinModelPortaliQ6CYV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

The N- and C-terminal flexible termini are involved in oligomerization and in the binding of non-native substrate proteins, and are essential for chaperone activity.UniRule annotation

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108SHS. Bacteria.
COG0071. LUCA.
HOGENOMiHOG000251750.
KOiK04081.
OMAiSDAHFEN.
OrthoDBiPOG091H0I9T.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
HAMAPiMF_02001. HSP20_IbpB. 1 hit.
InterProiIPR002068. A-crystallin/Hsp20_dom.
IPR031107. HSP20.
IPR008978. HSP20-like_chaperone.
IPR022848. HSP20_IbpB.
[Graphical view]
PANTHERiPTHR11527. PTHR11527. 1 hit.
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6CYV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNYDLSPLL RQWIGFDKLA SSMQGSQEPI DFPPYNIEKK DDNHYRITLA
60 70 80 90 100
LAGFRQSDLD IEVEGPRLTV KGSPAPSEKA VEYLHQGLVF KPFTLSFTLA
110 120 130 140 150
EHLHVSDAHF ENGLLHIDLV RDVPEALQPQ RIAIGGGRPA LNQQSAEDAS
Length:150
Mass (Da):16,762
Last modified:August 16, 2004 - v1
Checksum:iE89AB987979E107A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950851 Genomic DNA. Translation: CAG77298.1.
RefSeqiWP_011095863.1. NC_004547.2.

Genome annotation databases

EnsemblBacteriaiCAG77298; CAG77298; ECA4402.
GeneIDi2882903.
KEGGieca:ECA4402.
PATRICi20484305. VBIPecAtr54885_4488.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950851 Genomic DNA. Translation: CAG77298.1.
RefSeqiWP_011095863.1. NC_004547.2.

3D structure databases

ProteinModelPortaliQ6CYV3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi218491.ECA4402.

Proteomic databases

PRIDEiQ6CYV3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAG77298; CAG77298; ECA4402.
GeneIDi2882903.
KEGGieca:ECA4402.
PATRICi20484305. VBIPecAtr54885_4488.

Phylogenomic databases

eggNOGiENOG4108SHS. Bacteria.
COG0071. LUCA.
HOGENOMiHOG000251750.
KOiK04081.
OMAiSDAHFEN.
OrthoDBiPOG091H0I9T.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
HAMAPiMF_02001. HSP20_IbpB. 1 hit.
InterProiIPR002068. A-crystallin/Hsp20_dom.
IPR031107. HSP20.
IPR008978. HSP20-like_chaperone.
IPR022848. HSP20_IbpB.
[Graphical view]
PANTHERiPTHR11527. PTHR11527. 1 hit.
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiIBPB_PECAS
AccessioniPrimary (citable) accession number: Q6CYV3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: August 16, 2004
Last modified: November 2, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.