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Protein

Small heat shock protein IbpB

Gene

ibpB

Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.UniRule annotation

Keywordsi

Molecular functionChaperone
Biological processStress response

Names & Taxonomyi

Protein namesi
Recommended name:
Small heat shock protein IbpBUniRule annotation
Alternative name(s):
16 kDa heat shock protein BUniRule annotation
Gene namesi
Name:ibpBUniRule annotation
Ordered Locus Names:ECA4402
OrganismiPectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Taxonomic identifieri218491 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaePectobacterium
Proteomesi
  • UP000007966 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001260311 – 150Small heat shock protein IbpBAdd BLAST150

Proteomic databases

PRIDEiQ6CYV3

Interactioni

Subunit structurei

Homodimer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to oligomers at high temperatures or high ionic concentrations. The decrease in size of the multimers is accompanied by an increase in chaperone activity.UniRule annotation

Protein-protein interaction databases

STRINGi218491.ECA4402

Structurei

3D structure databases

ProteinModelPortaliQ6CYV3
SMRiQ6CYV3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 137sHSPPROSITE-ProRule annotationAdd BLAST112

Domaini

The N- and C-terminal flexible termini are involved in oligomerization and in the binding of non-native substrate proteins, and are essential for chaperone activity.UniRule annotation

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108SHS Bacteria
COG0071 LUCA
HOGENOMiHOG000251750
KOiK04081
OMAiLVFKPFT
OrthoDBiPOG091H0I9T

Family and domain databases

CDDicd06470 ACD_IbpA-B_like, 1 hit
Gene3Di2.60.40.790, 1 hit
HAMAPiMF_02001 HSP20_IbpB, 1 hit
InterProiView protein in InterPro
IPR002068 A-crystallin/Hsp20_dom
IPR037913 ACD_IbpA/B
IPR031107 HSP20
IPR008978 HSP20-like_chaperone
IPR022848 HSP20_IbpB
PANTHERiPTHR11527 PTHR11527, 1 hit
PfamiView protein in Pfam
PF00011 HSP20, 1 hit
SUPFAMiSSF49764 SSF49764, 1 hit
PROSITEiView protein in PROSITE
PS01031 SHSP, 1 hit

Sequencei

Sequence statusi: Complete.

Q6CYV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNYDLSPLL RQWIGFDKLA SSMQGSQEPI DFPPYNIEKK DDNHYRITLA
60 70 80 90 100
LAGFRQSDLD IEVEGPRLTV KGSPAPSEKA VEYLHQGLVF KPFTLSFTLA
110 120 130 140 150
EHLHVSDAHF ENGLLHIDLV RDVPEALQPQ RIAIGGGRPA LNQQSAEDAS
Length:150
Mass (Da):16,762
Last modified:August 16, 2004 - v1
Checksum:iE89AB987979E107A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950851 Genomic DNA Translation: CAG77298.1
RefSeqiWP_011095863.1, NC_004547.2

Genome annotation databases

EnsemblBacteriaiCAG77298; CAG77298; ECA4402
KEGGieca:ECA4402

Similar proteinsi

Entry informationi

Entry nameiIBPB_PECAS
AccessioniPrimary (citable) accession number: Q6CYV3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: August 16, 2004
Last modified: February 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health