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Q6CX53

- GLGB_KLULA

UniProt

Q6CX53 - GLGB_KLULA

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Protein

1,4-alpha-glucan-branching enzyme

Gene
GLC3, KLLA0A11176g
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei364 – 3641Nucleophile By similarity
Active sitei425 – 4251Proton donor By similarity

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-EC
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan-branching enzyme (EC:2.4.1.18)
Alternative name(s):
Glycogen-branching enzyme
Gene namesi
Name:GLC3
Ordered Locus Names:KLLA0A11176g
OrganismiKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Taxonomic identifieri284590 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces
ProteomesiUP000000598: Chromosome A

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7197191,4-alpha-glucan-branching enzymePRO_0000188784Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi28985.Q6CX53.

Structurei

3D structure databases

ProteinModelPortaliQ6CX53.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000175159.
KOiK00700.
OMAiGPRGTHD.
OrthoDBiEOG7647B5.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6CX53-1 [UniParc]FASTAAdd to Basket

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MTGDNNDIPE NVRGVVEIDS WLTPFAKVLS ERRYLADEWR YKIEHSTNSE    50
GRDTTLAQFA RDAYKSFGLH ADPGSLEIRY KEWAPNAVRA FLIGEFNSWN 100
ENANEMQRDE YGIFTTVVPP VVDDSGNKQY GIPHDSKVKV CFQLADGSRI 150
YRLPAWITRA TQPDKETAKQ WGPSYEARFW NPPVHYSFKN KRPGFMRDTD 200
SLRIYEAHVG ISTPEPKVGS YKEFTQNVLP RIKDLGYDAI QLMAIMEHAY 250
YASFGYQVTN FFAASSRFGT PDELKELVDT AHGMGILVLL DVVHSHASKN 300
VTDGLNQFDG SDHQYFHSLA SSRGEHPLWD SRLFNYGHFE VQRFLLANLA 350
FYIDVYQFDG FRFDGVTSML YLHHGVGEGG AFSGDYNEYL SSERSFVDHE 400
ALAYLMLAND LVRELLPDNG ITIAEDVSGY PTLCMPRHLG GAGFDYRLAM 450
ALPDMWIKLL KESRDEDWEM GHIVHTLVNR RHREKVVAYT ESHDQALVGD 500
KTLAFWLMDA AMYTDMTILK ESTPVVDRGI ALHKLIRLIT HSLGGEAYLN 550
FEGNEFGHPE WLDFPNVNNG DSYHYARRQF NLVDDPLLRY QYLYQFDKAM 600
QTTEKNYKWL NTPQAYVSLK HEVDKVIAFE RNGLLFIFNF HPTESFTDYR 650
IGVNEPGCYR IVLNSDKHEY GGWDRIDESQ SKYFTTDLKW NERNNFIQVY 700
IPNRTALVLA LDSRVRNGN 719
Length:719
Mass (Da):82,857
Last modified:August 16, 2004 - v1
Checksum:iCE6B5780568A37D9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR382121 Genomic DNA. Translation: CAH03074.1.
RefSeqiXP_451486.1. XM_451486.1.

Genome annotation databases

GeneIDi2896528.
KEGGikla:KLLA0A11176g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR382121 Genomic DNA. Translation: CAH03074.1 .
RefSeqi XP_451486.1. XM_451486.1.

3D structure databases

ProteinModelPortali Q6CX53.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 28985.Q6CX53.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2896528.
KEGGi kla:KLLA0A11176g.

Phylogenomic databases

eggNOGi COG0296.
HOGENOMi HOG000175159.
KOi K00700.
OMAi GPRGTHD.
OrthoDBi EOG7647B5.

Enzyme and pathway databases

UniPathwayi UPA00164 .

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProi IPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view ]
PIRSFi PIRSF000463. GlgB. 1 hit.
SUPFAMi SSF51445. SSF51445. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNeti Search...

Entry informationi

Entry nameiGLGB_KLULA
AccessioniPrimary (citable) accession number: Q6CX53
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: August 16, 2004
Last modified: May 14, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi