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Q6CX53

- GLGB_KLULA

UniProt

Q6CX53 - GLGB_KLULA

Protein

1,4-alpha-glucan-branching enzyme

Gene

GLC3

Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (16 Aug 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei364 – 3641NucleophileBy similarity
    Active sitei425 – 4251Proton donorBy similarity

    GO - Molecular functioni

    1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-EC
    2. cation binding Source: InterPro
    3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

    GO - Biological processi

    1. glycogen biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Glycogen biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00164.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    1,4-alpha-glucan-branching enzyme (EC:2.4.1.18)
    Alternative name(s):
    Glycogen-branching enzyme
    Gene namesi
    Name:GLC3
    Ordered Locus Names:KLLA0A11176g
    OrganismiKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
    Taxonomic identifieri284590 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces
    ProteomesiUP000000598: Chromosome A

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7197191,4-alpha-glucan-branching enzymePRO_0000188784Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi28985.Q6CX53.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6CX53.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0296.
    HOGENOMiHOG000175159.
    KOiK00700.
    OMAiGPRGTHD.
    OrthoDBiEOG7647B5.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    2.60.40.1180. 1 hit.
    3.20.20.80. 1 hit.
    InterProiIPR006048. A-amylase_b_C.
    IPR006407. GlgB.
    IPR015902. Glyco_hydro_13.
    IPR013780. Glyco_hydro_13_b.
    IPR006047. Glyco_hydro_13_cat_dom.
    IPR004193. Glyco_hydro_13_N.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    [Graphical view]
    PANTHERiPTHR10357. PTHR10357. 1 hit.
    PfamiPF00128. Alpha-amylase. 1 hit.
    PF02806. Alpha-amylase_C. 1 hit.
    PF02922. CBM_48. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000463. GlgB. 1 hit.
    SUPFAMiSSF51445. SSF51445. 2 hits.
    SSF81296. SSF81296. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q6CX53-1 [UniParc]FASTAAdd to Basket

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    MTGDNNDIPE NVRGVVEIDS WLTPFAKVLS ERRYLADEWR YKIEHSTNSE    50
    GRDTTLAQFA RDAYKSFGLH ADPGSLEIRY KEWAPNAVRA FLIGEFNSWN 100
    ENANEMQRDE YGIFTTVVPP VVDDSGNKQY GIPHDSKVKV CFQLADGSRI 150
    YRLPAWITRA TQPDKETAKQ WGPSYEARFW NPPVHYSFKN KRPGFMRDTD 200
    SLRIYEAHVG ISTPEPKVGS YKEFTQNVLP RIKDLGYDAI QLMAIMEHAY 250
    YASFGYQVTN FFAASSRFGT PDELKELVDT AHGMGILVLL DVVHSHASKN 300
    VTDGLNQFDG SDHQYFHSLA SSRGEHPLWD SRLFNYGHFE VQRFLLANLA 350
    FYIDVYQFDG FRFDGVTSML YLHHGVGEGG AFSGDYNEYL SSERSFVDHE 400
    ALAYLMLAND LVRELLPDNG ITIAEDVSGY PTLCMPRHLG GAGFDYRLAM 450
    ALPDMWIKLL KESRDEDWEM GHIVHTLVNR RHREKVVAYT ESHDQALVGD 500
    KTLAFWLMDA AMYTDMTILK ESTPVVDRGI ALHKLIRLIT HSLGGEAYLN 550
    FEGNEFGHPE WLDFPNVNNG DSYHYARRQF NLVDDPLLRY QYLYQFDKAM 600
    QTTEKNYKWL NTPQAYVSLK HEVDKVIAFE RNGLLFIFNF HPTESFTDYR 650
    IGVNEPGCYR IVLNSDKHEY GGWDRIDESQ SKYFTTDLKW NERNNFIQVY 700
    IPNRTALVLA LDSRVRNGN 719
    Length:719
    Mass (Da):82,857
    Last modified:August 16, 2004 - v1
    Checksum:iCE6B5780568A37D9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR382121 Genomic DNA. Translation: CAH03074.1.
    RefSeqiXP_451486.1. XM_451486.1.

    Genome annotation databases

    GeneIDi2896528.
    KEGGikla:KLLA0A11176g.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR382121 Genomic DNA. Translation: CAH03074.1 .
    RefSeqi XP_451486.1. XM_451486.1.

    3D structure databases

    ProteinModelPortali Q6CX53.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 28985.Q6CX53.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2896528.
    KEGGi kla:KLLA0A11176g.

    Phylogenomic databases

    eggNOGi COG0296.
    HOGENOMi HOG000175159.
    KOi K00700.
    OMAi GPRGTHD.
    OrthoDBi EOG7647B5.

    Enzyme and pathway databases

    UniPathwayi UPA00164 .

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    2.60.40.1180. 1 hit.
    3.20.20.80. 1 hit.
    InterProi IPR006048. A-amylase_b_C.
    IPR006407. GlgB.
    IPR015902. Glyco_hydro_13.
    IPR013780. Glyco_hydro_13_b.
    IPR006047. Glyco_hydro_13_cat_dom.
    IPR004193. Glyco_hydro_13_N.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    [Graphical view ]
    PANTHERi PTHR10357. PTHR10357. 1 hit.
    Pfami PF00128. Alpha-amylase. 1 hit.
    PF02806. Alpha-amylase_C. 1 hit.
    PF02922. CBM_48. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000463. GlgB. 1 hit.
    SUPFAMi SSF51445. SSF51445. 2 hits.
    SSF81296. SSF81296. 1 hit.
    ProtoNeti Search...

    Entry informationi

    Entry nameiGLGB_KLULA
    AccessioniPrimary (citable) accession number: Q6CX53
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 10, 2005
    Last sequence update: August 16, 2004
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3