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Q6CWJ6 (QCR2_KLULA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome b-c1 complex subunit 2, mitochondrial
Alternative name(s):
Complex III subunit 2
Core protein II
Ubiquinol-cytochrome-c reductase complex core protein 2
Gene names
Name:QCR2
Ordered Locus Names:KLLA0B03564g
OrganismKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) [Complete proteome]
Taxonomic identifier284590 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces

Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex By similarity.

Subunit structure

Fungi bc1 complex contains 10 subunits; 3 respiratory subunits, 2 core proteins and 5 low-molecular weight proteins By similarity.

Subcellular location

Mitochondrion inner membrane By similarity.

Sequence similarities

Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.

Caution

Does not seem to have a protease activity as it lack the zinc-binding site.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 1515Mitochondrion By similarity
Chain16 – 360345Cytochrome b-c1 complex subunit 2, mitochondrial
PRO_0000026797

Sequences

Sequence LengthMass (Da)Tools
Q6CWJ6 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 0E5B9D6D6AB18A4A

FASTA36039,248
        10         20         30         40         50         60 
MLSSRLQFAQ QTARKFSISA KDGSGKLSTL AVKVHGGSRY ADKEGIAHLL SRFNFHNTGN 

        70         80         90        100        110        120 
KSALRLVRES ELLGGKFESS VDREYITLKA TFLKEDLPYF VNALGNVLYK TSFRPHELPE 

       130        140        150        160        170        180 
SVLPAAKYDI SVSETNPINK AEDLLYNVSF RKDLGNTVLY RGVEKVTLDD IKAYANKVYT 

       190        200        210        220        230        240 
KENIEIVGQG VNEADLKRFV NDSLIGSLPT GSKLAAQAQP KFFSGEARLS APGASVAAIA 

       250        260        270        280        290        300 
VPVTKEQFAT YEVLAKYLTS ALSELSPLID SAKLDKYANA GLFSLYVKGE DASVVAENIK 

       310        320        330        340        350        360 
KVVDTLKKDV DISAAKEYTA LQLSLENAPI DVSNVKNVKL DKFSYAAVGN VAKLPFADEL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382122 Genomic DNA. Translation: CAH02086.1.
RefSeqXP_451693.1. XM_451693.1.

3D structure databases

ProteinModelPortalQ6CWJ6.
SMRQ6CWJ6. Positions 16-360.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING28985.Q6CWJ6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2897081.
KEGGkla:KLLA0B03564g.

Phylogenomic databases

eggNOGCOG0612.
HOGENOMHOG000159494.
KOK00415.
OMAYITLKAT.
OrthoDBEOG7F51BJ.

Family and domain databases

Gene3D3.30.830.10. 2 hits.
InterProIPR011249. Metalloenz_LuxS/M16.
IPR011237. Pept_M16_dom.
IPR011765. Pept_M16_N.
IPR007863. Peptidase_M16_C.
[Graphical view]
PfamPF00675. Peptidase_M16. 1 hit.
PF05193. Peptidase_M16_C. 1 hit.
[Graphical view]
SUPFAMSSF63411. SSF63411. 2 hits.
ProtoNetSearch...

Entry information

Entry nameQCR2_KLULA
AccessionPrimary (citable) accession number: Q6CWJ6
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: August 16, 2004
Last modified: November 13, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries