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Q6CUK3 (Q6CUK3_KLULA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase RuleBase RU000613
EC=6.3.2.6 RuleBase RU000613
Gene names
Ordered Locus Names:KLLA0C04235g
OrganismKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) [Complete proteome]
Taxonomic identifier284590 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Kluyveromyces

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. RuleBase RU000613

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. RuleBase RU000613

Sequence similarities

Belongs to the SAICAR synthetase family. RuleBase RU004193

Sequences

Sequence LengthMass (Da)Tools
Q6CUK3 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 3464FC82164B82D9

FASTA30935,058
        10         20         30         40         50         60 
MNTTSITQTN LDGILPLVAR GKVRDIYQVD DQTLLFVATD RISAYDVIMK NAIPEKGILL 

        70         80         90        100        110        120 
TKLSEFWFDF LKEDVRNHLK PLGPGETIFD KLPAKLSESK YKVQLEGRSL LVQKHKLIPL 

       130        140        150        160        170        180 
EVIVRGFITG SAWKEYKKTG TVHGLPQPEG LLESQEFPSP IFTPSTKAEQ GEHDENISPE 

       190        200        210        220        230        240 
QAARLVGQDL CDRIEKLAIK LYTKCKDFAK SRGIIIADTK FEFGIDESTN EIILVDEVLT 

       250        260        270        280        290        300 
PDSSRFWNGT NFEVGKTQDS YDKQFLRNWL TDNKLAGVDG VEMPQDIADR TRSKYIEAYE 


QITGQKWNI

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR382123 Genomic DNA. Translation: CAH01237.1.
RefSeqXP_452386.1. XM_452386.1.

3D structure databases

ProteinModelPortalQ6CUK3.
SMRQ6CUK3. Positions 5-308.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6CUK3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2892265.
GenomeReviewsGene locus KLLA0C04235g in contig CR382123_GR.
KEGGkla:KLLA0C04235g.

Phylogenomic databases

eggNOGfuNOG04520.
HOGENOMHBG555040.
OMASSRIWDG.
OrthoDBEOG4JMBZN.

Family and domain databases

HAMAPMF_00137. SAICAR_synth.
[Tree]
InterProIPR013816. ATP_grasp_subdomain_2.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
Gene3DG3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KOK01923.
PANTHERPTHR11609. SAICAR_synt. 1 hit.
PfamPF01259. SAICAR_synt. 1 hit.
[Graphical view]
TIGRFAMsTIGR00081. PurC. 1 hit.
PROSITEPS01057. SAICAR_SYNTHETASE_1. 1 hit.
PS01058. SAICAR_SYNTHETASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6CUK3_KLULA
AccessionPrimary (citable) accession number: Q6CUK3
Entry history
Integrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: December 14, 2011
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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