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Q6CTE4

- OCA1_KLULA

UniProt

Q6CTE4 - OCA1_KLULA

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Protein

Putative tyrosine-protein phosphatase OCA1

Gene
OCA1, KLLA0C13343g
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Putative tyrosine-protein phosphatase required for protection against superoxide stress By similarity.

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei140 – 1401Phosphocysteine intermediate By similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC

GO - Biological processi

  1. response to stress Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
Gene namesi
Name:OCA1
Ordered Locus Names:KLLA0C13343g
OrganismiKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Taxonomic identifieri284590 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces
ProteomesiUP000000598: Chromosome C

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 210210Putative tyrosine-protein phosphatase OCA1PRO_0000333392Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi28985.Q6CTE4.

Structurei

3D structure databases

ProteinModelPortaliQ6CTE4.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2365.
HOGENOMiHOG000188365.
KOiK18043.
OMAiNSHSINI.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSiPR01911. PFDSPHPHTASE.
SUPFAMiSSF52799. SSF52799. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6CTE4-1 [UniParc]FASTAAdd to Basket

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MSAIDNYQDE EEDDIVCVNE EIETGHPRVT ILHPPNERIV PPLNFCPVER    50
YLYRSGQPSN VNFPFLLNLK LKTIIWLANE EPQDALLEFC DDHNIQLQFA 100
AINPDGGEDD NPWDGLTEHS IRNALHTIVN SESYPLLVCC GMGRHRTGTV 150
IGCLRRLMGW NLASVSEEYR RFTGSRGGRI LVELLIEAFD ITSVEIDREK 200
APNWLLTALS 210
Length:210
Mass (Da):23,846
Last modified:August 16, 2004 - v1
Checksum:i5363C3ED57EBDD0E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR382123 Genomic DNA. Translation: CAH01646.1.
RefSeqiXP_452795.1. XM_452795.1.

Genome annotation databases

GeneIDi2891920.
KEGGikla:KLLA0C13343g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR382123 Genomic DNA. Translation: CAH01646.1 .
RefSeqi XP_452795.1. XM_452795.1.

3D structure databases

ProteinModelPortali Q6CTE4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 28985.Q6CTE4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2891920.
KEGGi kla:KLLA0C13343g.

Phylogenomic databases

eggNOGi COG2365.
HOGENOMi HOG000188365.
KOi K18043.
OMAi NSHSINI.
OrthoDBi EOG7Z0K6V.

Family and domain databases

Gene3Di 3.90.190.10. 1 hit.
InterProi IPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view ]
Pfami PF03162. Y_phosphatase2. 1 hit.
[Graphical view ]
PRINTSi PR01911. PFDSPHPHTASE.
SUPFAMi SSF52799. SSF52799. 1 hit.
ProtoNeti Search...

Entry informationi

Entry nameiOCA1_KLULA
AccessioniPrimary (citable) accession number: Q6CTE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 16, 2004
Last modified: June 11, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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