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Q6CTE4

- OCA1_KLULA

UniProt

Q6CTE4 - OCA1_KLULA

Protein

Putative tyrosine-protein phosphatase OCA1

Gene

OCA1

Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (16 Aug 2004)
      Previous versions | rss
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    Functioni

    Putative tyrosine-protein phosphatase required for protection against superoxide stress.By similarity

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei140 – 1401Phosphocysteine intermediateBy similarity

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    GO - Biological processi

    1. response to stress Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Biological processi

    Stress response

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
    Gene namesi
    Name:OCA1
    Ordered Locus Names:KLLA0C13343g
    OrganismiKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
    Taxonomic identifieri284590 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces
    ProteomesiUP000000598: Chromosome C

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 210210Putative tyrosine-protein phosphatase OCA1PRO_0000333392Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi28985.Q6CTE4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6CTE4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG2365.
    HOGENOMiHOG000188365.
    KOiK18043.
    OMAiNSHSINI.
    OrthoDBiEOG7Z0K6V.

    Family and domain databases

    Gene3Di3.90.190.10. 1 hit.
    InterProiIPR029021. Prot-tyrosine_phosphatase-like.
    IPR020428. Tyr_Pase_dualsp-Pase_euk.
    IPR004861. Tyr_Pase_SIW14-like.
    [Graphical view]
    PfamiPF03162. Y_phosphatase2. 1 hit.
    [Graphical view]
    PRINTSiPR01911. PFDSPHPHTASE.
    SUPFAMiSSF52799. SSF52799. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q6CTE4-1 [UniParc]FASTAAdd to Basket

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    MSAIDNYQDE EEDDIVCVNE EIETGHPRVT ILHPPNERIV PPLNFCPVER    50
    YLYRSGQPSN VNFPFLLNLK LKTIIWLANE EPQDALLEFC DDHNIQLQFA 100
    AINPDGGEDD NPWDGLTEHS IRNALHTIVN SESYPLLVCC GMGRHRTGTV 150
    IGCLRRLMGW NLASVSEEYR RFTGSRGGRI LVELLIEAFD ITSVEIDREK 200
    APNWLLTALS 210
    Length:210
    Mass (Da):23,846
    Last modified:August 16, 2004 - v1
    Checksum:i5363C3ED57EBDD0E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR382123 Genomic DNA. Translation: CAH01646.1.
    RefSeqiXP_452795.1. XM_452795.1.

    Genome annotation databases

    GeneIDi2891920.
    KEGGikla:KLLA0C13343g.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR382123 Genomic DNA. Translation: CAH01646.1 .
    RefSeqi XP_452795.1. XM_452795.1.

    3D structure databases

    ProteinModelPortali Q6CTE4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 28985.Q6CTE4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2891920.
    KEGGi kla:KLLA0C13343g.

    Phylogenomic databases

    eggNOGi COG2365.
    HOGENOMi HOG000188365.
    KOi K18043.
    OMAi NSHSINI.
    OrthoDBi EOG7Z0K6V.

    Family and domain databases

    Gene3Di 3.90.190.10. 1 hit.
    InterProi IPR029021. Prot-tyrosine_phosphatase-like.
    IPR020428. Tyr_Pase_dualsp-Pase_euk.
    IPR004861. Tyr_Pase_SIW14-like.
    [Graphical view ]
    Pfami PF03162. Y_phosphatase2. 1 hit.
    [Graphical view ]
    PRINTSi PR01911. PFDSPHPHTASE.
    SUPFAMi SSF52799. SSF52799. 1 hit.
    ProtoNeti Search...

    Entry informationi

    Entry nameiOCA1_KLULA
    AccessioniPrimary (citable) accession number: Q6CTE4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: August 16, 2004
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3