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Q6CTE4

- OCA1_KLULA

UniProt

Q6CTE4 - OCA1_KLULA

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Protein

Putative tyrosine-protein phosphatase OCA1

Gene

OCA1

Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Putative tyrosine-protein phosphatase required for protection against superoxide stress.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei140 – 1401Phosphocysteine intermediateBy similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC

GO - Biological processi

  1. response to stress Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
Gene namesi
Name:OCA1
Ordered Locus Names:KLLA0C13343g
OrganismiKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Taxonomic identifieri284590 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces
ProteomesiUP000000598: Chromosome C

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 210210Putative tyrosine-protein phosphatase OCA1PRO_0000333392Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi28985.Q6CTE4.

Structurei

3D structure databases

ProteinModelPortaliQ6CTE4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2365.
HOGENOMiHOG000188365.
InParanoidiQ6CTE4.
KOiK18043.
OMAiNSHSINI.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSiPR01911. PFDSPHPHTASE.
SUPFAMiSSF52799. SSF52799. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6CTE4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSAIDNYQDE EEDDIVCVNE EIETGHPRVT ILHPPNERIV PPLNFCPVER
60 70 80 90 100
YLYRSGQPSN VNFPFLLNLK LKTIIWLANE EPQDALLEFC DDHNIQLQFA
110 120 130 140 150
AINPDGGEDD NPWDGLTEHS IRNALHTIVN SESYPLLVCC GMGRHRTGTV
160 170 180 190 200
IGCLRRLMGW NLASVSEEYR RFTGSRGGRI LVELLIEAFD ITSVEIDREK
210
APNWLLTALS
Length:210
Mass (Da):23,846
Last modified:August 16, 2004 - v1
Checksum:i5363C3ED57EBDD0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382123 Genomic DNA. Translation: CAH01646.1.
RefSeqiXP_452795.1. XM_452795.1.

Genome annotation databases

GeneIDi2891920.
KEGGikla:KLLA0C13343g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382123 Genomic DNA. Translation: CAH01646.1 .
RefSeqi XP_452795.1. XM_452795.1.

3D structure databases

ProteinModelPortali Q6CTE4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 28985.Q6CTE4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2891920.
KEGGi kla:KLLA0C13343g.

Phylogenomic databases

eggNOGi COG2365.
HOGENOMi HOG000188365.
InParanoidi Q6CTE4.
KOi K18043.
OMAi NSHSINI.
OrthoDBi EOG7Z0K6V.

Family and domain databases

Gene3Di 3.90.190.10. 1 hit.
InterProi IPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view ]
Pfami PF03162. Y_phosphatase2. 1 hit.
[Graphical view ]
PRINTSi PR01911. PFDSPHPHTASE.
SUPFAMi SSF52799. SSF52799. 1 hit.
ProtoNeti Search...

Entry informationi

Entry nameiOCA1_KLULA
AccessioniPrimary (citable) accession number: Q6CTE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 16, 2004
Last modified: October 29, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3