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Q6CT57 (RIFK_KLULA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Riboflavin kinase

EC=2.7.1.26
Alternative name(s):
Flavin mononucleotide kinase 1
Gene names
Name:FMN1
Ordered Locus Names:KLLA0C15213g
OrganismKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) [Complete proteome]
Taxonomic identifier284590 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces

Protein attributes

Sequence length185 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme By similarity.

Catalytic activity

ATP + riboflavin = ADP + FMN.

Cofactor

Zinc or magnesium By similarity.

Pathway

Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.

Sequence similarities

Belongs to the flavokinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 185185Riboflavin kinase
PRO_0000301842

Sites

Active site1221Nucleophile By similarity
Metal binding411Magnesium or zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6CT57 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 6ECE5B40481696DA

FASTA18520,939
        10         20         30         40         50         60 
MTRHCDVSIP DSPEPPFPIT TSFVDVIAGF GRGSAELGIP TANVPIDDLP KIVEQLDTGV 

        70         80         90        100        110        120 
YFGWCKVRMA KDRDTKVEQR PDGREVQYNN GTLLNDEDLA VLPVVLSVGW NPFYQNKNKT 

       130        140        150        160        170        180 
VELHIIHKFS DNFYGAQIKF NFLGYIRPEL DYTTKDALIA DIHTDIEIAK EKLQLPGYRK 


LKDTL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382123 Genomic DNA. Translation: CAH01733.1.
RefSeqXP_452882.1. XM_452882.1.

3D structure databases

ProteinModelPortalQ6CT57.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING28985.Q6CT57.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2891986.
KEGGkla:KLLA0C15213g.

Phylogenomic databases

eggNOGCOG0196.
HOGENOMHOG000260803.
KOK00861.
OMALGWNPFY.
OrthoDBEOG7K3V05.

Enzyme and pathway databases

UniPathwayUPA00276; UER00406.

Family and domain databases

Gene3D2.40.30.30. 1 hit.
InterProIPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PANTHERPTHR22749. PTHR22749. 1 hit.
PfamPF01687. Flavokinase. 1 hit.
[Graphical view]
SMARTSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMSSF82114. SSF82114. 2 hits.
ProtoNetSearch...

Entry information

Entry nameRIFK_KLULA
AccessionPrimary (citable) accession number: Q6CT57
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: August 16, 2004
Last modified: January 22, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways