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Q6CSY3 (ALO_KLULA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-arabinono-1,4-lactone oxidase

Short name=ALO
EC=1.1.3.37
Alternative name(s):
L-galactono-gamma-lactone oxidase
Gene names
Name:ALO1
Ordered Locus Names:KLLA0C16896g
OrganismKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) [Complete proteome]
Taxonomic identifier284590 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces

Protein attributes

Sequence length525 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2.

Cofactor

FAD By similarity.

Pathway

Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.

Subcellular location

Mitochondrion membrane By similarity. Note: Membrane-embedded By similarity.

Sequence similarities

Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

Contains 1 FAD-binding PCMH-type domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 525525D-arabinono-1,4-lactone oxidase
PRO_0000128167

Regions

Domain23 – 197175FAD-binding PCMH-type

Amino acid modifications

Modified residue601Pros-8alpha-FAD histidine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6CSY3 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 2C3487B581F808E6

FASTA52559,206
        10         20         30         40         50         60 
MSFDLVAGNA RSNFVFKNWA GIYSCRPQLY FQPNSIDEVV QIVKAAIEQG KTIVTVGSGH 

        70         80         90        100        110        120 
SPSDMCVTDQ WLMNLDNLNS VVEFKENKEE LYADVTVEAG LRIYQLSEIL AEKGYAIQNL 

       130        140        150        160        170        180 
GSISEQSVAG IISTGTHGSS PYHGLVSSQY VNLTIVNGKG EVVFLDSENS PEVFRAATLS 

       190        200        210        220        230        240 
LGKIGIIVKA TIRVIPEFNI KSTQEVIHFE TLLNNWETIW TSSEFIRCWW YPYTRKVVLW 

       250        260        270        280        290        300 
RGSKTEEPLT APRKSWWGST FGRFIYESLI WISVKIYPAL TPYVESFVFH QQYGRVETYG 

       310        320        330        340        350        360 
SGDVSVQTSI AGLNMDCLFS QFVDEWGCPL NNGPEVLRSL DYSITQAAQN KEFFVHVPVE 

       370        380        390        400        410        420 
VRCSNTTLPA EIPDYSNRTK TSAGPVFGNT LRPYLDATPR HLRYAPLSDV TNSQLSLYIN 

       430        440        450        460        470        480 
ATIYRPFGSN SPIHKWFTLF EDTMGAAGGK PHWAKNFLGA TSMAAGKVKD EKDYDDYEMR 

       490        500        510        520 
GMATKIKEWY GEDLLKFREI RSQQDPNNVF MANKEWAIRN GIIEP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382123 Genomic DNA. Translation: CAH01807.1.
RefSeqXP_452956.1. XM_452956.1.

3D structure databases

ProteinModelPortalQ6CSY3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING28985.Q6CSY3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2892284.
KEGGkla:KLLA0C16896g.

Phylogenomic databases

eggNOGCOG0277.
HOGENOMHOG000204635.
KOK00107.
OMAMDCLFSQ.
OrthoDBEOG7JX3CZ.

Enzyme and pathway databases

UniPathwayUPA00771; UER00766.

Family and domain databases

Gene3D3.30.43.10. 1 hit.
3.30.465.10. 1 hit.
InterProIPR007173. ALO.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR016167. FAD-bd_2_sub1.
IPR010031. FAD_lactone_oxidase.
IPR023595. LGO_GLO.
IPR006094. Oxid_FAD_bind_N.
IPR006093. Oxy_OxRdtase_FAD_BS.
[Graphical view]
PfamPF04030. ALO. 1 hit.
PF01565. FAD_binding_4. 1 hit.
[Graphical view]
PIRSFPIRSF000136. LGO_GLO. 1 hit.
SUPFAMSSF56176. SSF56176. 1 hit.
TIGRFAMsTIGR01678. FAD_lactone_ox. 1 hit.
PROSITEPS51387. FAD_PCMH. 1 hit.
PS00862. OX2_COVAL_FAD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALO_KLULA
AccessionPrimary (citable) accession number: Q6CSY3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: August 16, 2004
Last modified: November 13, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways