Q6CST5 (Q6CST5_KLULA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cysteine synthase RuleBase RU003985
EC=2.5.1.47 RuleBase RU003985

Gene names

Ordered Locus Names:

KLLA0C18029g

Organism

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) [Complete proteome]

Taxonomic identifier

284590 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Kluyveromyces

Protein attributes

Sequence length	384 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. RuleBase RU003985
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis RuleBase RU003985
Molecular function	Transferase RuleBase RU003985
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular function	cysteine synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6CST5 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 28176A7D854919AC	FASTA	384	41,717
	10 20 30 40 50 60 MTAADRWKDY ACVTSLFVAV ASLYYAYKVK TTTLTALSPP KDGVEDLIGN TPMVRIKSLS 70 80 90 100 110 120 DYTGLNVFAK MELNNPGGSA KDRVALNIIK TISSQEGIKG SSDKKNRIFE GTSGSTGISL 130 140 150 160 170 180 AICCNALGYS CHISLPDDTS QEKLSLLTAL GAIVNKVKPA SIVDPNQYVN AAKSCSEEYT 190 200 210 220 230 240 EGVGVFADQF ENEANWKCHY ETTGPEIYLQ LNGEVDAFIT GCGTGGTMAG VSRYLKEKRG 250 260 270 280 290 300 DKVHIVLADP QGSGFYNRIK YGVMYDNVEK EGTRRRHQVD TLVEGIGLNR ITNNFLKAEN 310 320 330 340 350 360 YIDDSIRITD EEAIKMAKFL CVNDGLFVGA STAINAVAVL KYAENLPKGS NVCIIACDSG 370 380 SRHLSKFWKE ALQVSNDLSI SDII

References

[1]

"Genome evolution in yeasts." Genolevures Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR382123 Genomic DNA. Translation: CAH01855.1.
RefSeq	XP_453004.1. XM_453004.1.
3D structure databases
ProteinModelPortal	Q6CST5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6CST5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2891904.
GenomeReviews	Gene locus KLLA0C18029g in contig CR382123_GR.
KEGG	kla:KLLA0C18029g.
Phylogenomic databases
eggNOG	fuNOG06015.
HOGENOM	HBG748215.
OMA	RVRPVSI.
OrthoDB	EOG45MRFC.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. IPR001926. PyrdxlP-dep_enz_bsu. [Graphical view]
Pfam	PF00291. PALP. 1 hit. [Graphical view]
SUPFAM	SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
PROSITE	PS00901. CYS_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6CST5_KLULA

Accession

Primary (citable) accession number: Q6CST5

Entry history

Integrated into UniProtKB/TrEMBL:	August 16, 2004
Last sequence update:	August 16, 2004
Last modified:	December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)