Q6CRT2 (Q6CRT2_KLULA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Nicotinate phosphoribosyltransferase RuleBase RU003838
EC=2.4.2.11 RuleBase RU003838

Gene names

Ordered Locus Names:

KLLA0D06655g

Organism

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) [Complete proteome]

Taxonomic identifier

284590 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Kluyveromyces

Protein attributes

Sequence length	427 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. RuleBase RU003838
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate ribonucleotide from nicotinate: step 1/1. RuleBase RU003838
Sequence similarities	Belongs to the NAPRTase family. RuleBase RU003838

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis RuleBase RU003838
Molecular function	Glycosyltransferase RuleBase RU003838 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: InterPro nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: EC nicotinate-nucleotide diphosphorylase (carboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6CRT2 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: D0F91565068C2267	FASTA	427	48,914
	10 20 30 40 50 60 MEPVITSFLD TDMYKLTMHA AVYTHFKDVK VKYKYTNRSP QMTFNKEAVE WLKGQFLLLA 70 80 90 100 110 120 NIRLTTEELK YIKEAIPYLP AEYLEFISNG GFEVNPKDEI KFEAREIEGE PGHYELDISI 130 140 150 160 170 180 EGLWIKTIWY EIPVLALVSE AYFKFVDTDW TYDGQVEKAY AKAKKLLDHD IVFSEFGTRR 190 200 210 220 230 240 RRSFKTQDLV MQGIINAAKD CDKSKYVLGT SNVLFAKKYN VNPIGTVAHE WMMGIASITN 250 260 270 280 290 300 DYLNANKNAM DYWIETFGME NAGLALTDTF GTDSFLKSFY PPYSDAYIGV RQDSGDPILY 310 320 330 340 350 360 TEKIAHHYND VLKLPKFSKI ICYSDSLNPD RAIEYAQVAH KHGLKATFGI GTNFTNDFQR 370 380 390 400 410 420 KSDVSVKSEP LNIVIKLLEV NGNHAIKISD NLGKNMGDPE TVRRVKEELG YVERKYAGDN EAHRWAA

References

[1]

"Genome evolution in yeasts." Genolevures Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR382124 Genomic DNA. Translation: CAH00453.1.
RefSeq	XP_453357.1. XM_453357.1.
3D structure databases
ProteinModelPortal	Q6CRT2.
SMR	Q6CRT2. Positions 2-416.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6CRT2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2893586.
GenomeReviews	Gene locus KLLA0D06655g in contig CR382124_GR.
KEGG	kla:KLLA0D06655g.
Phylogenomic databases
eggNOG	fuNOG05269.
HOGENOM	HBG325503.
OMA	HQFPQTH.
OrthoDB	EOG479JGB.
Family and domain databases
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. IPR002638. Quinolinate_PRibosylTrfase_C. [Graphical view]
KO	K00763.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
SUPFAM	SSF51690. Q_phspho_trans. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q6CRT2_KLULA

Accession

Primary (citable) accession number: Q6CRT2

Entry history

Integrated into UniProtKB/TrEMBL:	August 16, 2004
Last sequence update:	August 16, 2004
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)