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Q6CR20

- Q6CR20_KLULA

UniProt

Q6CR20 - Q6CR20_KLULA

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Protein
DNA ligase
Gene
KLLA0D12496g, KLLA0_D12496g
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:KLLA0D12496gImported
ORF Names:KLLA0_D12496gImported
OrganismiKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Taxonomic identifieri284590 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces
ProteomesiUP000000598: Chromosome D

Interactioni

Protein-protein interaction databases

STRINGi28985.Q6CR20.

Structurei

3D structure databases

ProteinModelPortaliQ6CR20.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036006.
KOiK10747.
OMAiMVKMLEG.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6CR20-1 [UniParc]FASTAAdd to Basket

« Hide

MFRLPIIRNW IVQRPVTFKV PSQQMSTKRS KQLTLDGFLR PNKKQKVDEE    50
GDSAMPDETA AAPPVKSESS LSNITPPKSR GETLTPVPSK LKFHSNIPFA 100
ELCDTFQAIE VTSSRLAITA ICSKFLYSVL ERDPESLVPI TYLFIHKLGP 150
DYEPGLELGL GESLLIKTIS EACGKSIQQI RNKYREIGDL GEIAMQARNV 200
QPTMFKPKPL TVGEVFNNLV SIAKSNGKDS QSRKGSLIKK MLTACKGYEA 250
KFLIRSLESK LRIGLAEKTV LISVSKAILT HEHNGQEPST EMVEQAESLI 300
RDAFCQVPNY EMIINVALQY GIMNLNQHIK LRPGIPLQPM LAKPTKSISE 350
VLDRFQGTKF TCEYKYDGER AQVHLCRDGS MKIYSRNGED MTERYPEIDV 400
KHYVKDLGAT KSFIVDSEAV AWDQEQGKIL PFQVLSTRKR KGVELKDVKV 450
RVCLYAFDIL CLNDEPLINK SFHERRQILL DTFNGTQGQF DFANELTTTN 500
FDELQKYLDQ SVKDSCEGLM VKMLEGEESH YEPSKRSRNW LKLKKDYLEG 550
VGDSLDLVVL GAYYGRGKRT GTYGGFLLGC YNLDSEEFET CCKIGTGFSD 600
EMLQDLYTKL KDTTVEHPST NVIYDSSAPA DVWFEPSMLF EVLTADLSLS 650
PVYKAGFEAF GKGISLRFPR FVRIRDDKNV TDATSSDQVI EFYESQAHMK 700
Length:700
Mass (Da):79,060
Last modified:August 16, 2004 - v1
Checksum:iBA33DB9C7D3CE0E0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR382124 Genomic DNA. Translation: CAH00715.1.
RefSeqiXP_453619.1. XM_453619.1.

Genome annotation databases

GeneIDi2892839.
KEGGikla:KLLA0D12496g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR382124 Genomic DNA. Translation: CAH00715.1 .
RefSeqi XP_453619.1. XM_453619.1.

3D structure databases

ProteinModelPortali Q6CR20.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 28985.Q6CR20.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2892839.
KEGGi kla:KLLA0D12496g.

Phylogenomic databases

HOGENOMi HOG000036006.
KOi K10747.
OMAi MVKMLEG.
OrthoDBi EOG7TXKRG.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Entry informationi

Entry nameiQ6CR20_KLULA
AccessioniPrimary (citable) accession number: Q6CR20
Entry historyi
Integrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: May 14, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi