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Protein

40S ribosomal protein S6

Gene

RPS6

Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S6
Gene namesi
Name:RPS6
Ordered Locus Names:KLLA0E24090g
OrganismiKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Taxonomic identifieri284590 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces
Proteomesi
  • UP000000598 Componenti: Chromosome E

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001373371 – 23640S ribosomal protein S6Add BLAST236

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei232PhosphoserineSequence analysis1
Modified residuei233PhosphoserineSequence analysis1

Post-translational modificationi

Phosphorylated.By similarity

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi284590.XP_455035.1.

Structurei

Secondary structure

1236
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 7Combined sources6
Turni8 – 11Combined sources4
Beta strandi12 – 17Combined sources6
Helixi21 – 24Combined sources4
Helixi25 – 27Combined sources3
Beta strandi34 – 38Combined sources5
Turni39 – 41Combined sources3
Beta strandi49 – 60Combined sources12
Beta strandi69 – 71Combined sources3
Beta strandi73 – 77Combined sources5
Beta strandi79 – 83Combined sources5
Beta strandi93 – 98Combined sources6
Beta strandi104 – 115Combined sources12
Beta strandi124 – 126Combined sources3
Helixi138 – 145Combined sources8
Helixi154 – 156Combined sources3
Beta strandi160 – 166Combined sources7
Beta strandi168 – 171Combined sources4
Helixi181 – 222Combined sources42

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J80electron microscopy3.75G1-236[»]
3J81electron microscopy4.00G1-236[»]
3JAMelectron microscopy3.46G1-236[»]
3JAPelectron microscopy4.90G1-236[»]
3JAQelectron microscopy6.00G1-236[»]
5IT7electron microscopy3.60G1-226[»]
5IT9electron microscopy3.80G1-226[»]
SMRiQ6CM04.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1646. Eukaryota.
COG2125. LUCA.
HOGENOMiHOG000190952.
InParanoidiQ6CM04.
KOiK02991.
OMAiKGYIFRI.
OrthoDBiEOG092C4QCP.

Family and domain databases

InterProiView protein in InterPro
IPR014401. Ribosomal_S6_euk.
IPR001377. Ribosomal_S6e.
IPR018282. Ribosomal_S6e_CS.
PANTHERiPTHR11502. PTHR11502. 1 hit.
PfamiView protein in Pfam
PF01092. Ribosomal_S6e. 1 hit.
PIRSFiPIRSF002129. Ribosom_S6_euk. 1 hit.
SMARTiView protein in SMART
SM01405. Ribosomal_S6e. 1 hit.
PROSITEiView protein in PROSITE
PS00578. RIBOSOMAL_S6E. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6CM04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNISYPIN GTQKCIEIDD EHRVRVFYDK RIGQEVDGES VGDEFKGYVF
60 70 80 90 100
KIAGGNDKQG FPMKQGVLLP TRVKLLLAKG HSCYRPRRNG ERKRKSVRGA
110 120 130 140 150
IVGPDLAVLA LIITKKGEQE IEGITNDTVP KRLGPKRANN IRKFFGLTKE
160 170 180 190 200
DDVRDYVIRR EVTKGDKSYT KAPKIQRLVT PQRLQRKRQQ KSLKIKNAQA
210 220 230
QREAAAEYAQ LLAKRLSERK AEKAEVRKRR ASSLKA
Length:236
Mass (Da):26,912
Last modified:August 16, 2004 - v1
Checksum:iBC919D228C9CF77B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382125 Genomic DNA. Translation: CAH00122.1.
AJ504414 Genomic DNA. Translation: CAD43214.1.
RefSeqiXP_455035.1. XM_455035.1.

Genome annotation databases

EnsemblFungiiCAH00122; CAH00122; KLLA0_E24047g.
GeneIDi2894345.
KEGGikla:KLLA0E24047g.

Similar proteinsi

Entry informationi

Entry nameiRS6_KLULA
AccessioniPrimary (citable) accession number: Q6CM04
Secondary accession number(s): Q6HA22
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: August 16, 2004
Last modified: September 27, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families