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Q6CLS8

- Q6CLS8_KLULA

UniProt

Q6CLS8 - Q6CLS8_KLULA

Protein

Arginase

Gene

KLLA0F00704g

Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (16 Aug 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-arginine + H2O = L-ornithine + urea.UniRule annotation

    Cofactori

    Binds 2 manganese ions per subunit.UniRule annotation

    GO - Molecular functioni

    1. arginase activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. arginine metabolic process Source: InterPro

    Keywords - Molecular functioni

    HydrolaseUniRule annotation

    Keywords - Biological processi

    Arginine metabolismUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ArginaseUniRule annotation (EC:3.5.3.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:KLLA0F00704gImported
    ORF Names:KLLA0_F00704gImported
    OrganismiKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)Imported
    Taxonomic identifieri284590 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces
    ProteomesiUP000000598: Chromosome F

    Interactioni

    Protein-protein interaction databases

    STRINGi28985.Q6CLS8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6CLS8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the arginase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000204319.
    KOiK01476.
    OMAiKEQECDV.
    OrthoDBiEOG7X0VT2.

    Family and domain databases

    Gene3Di3.40.800.10. 1 hit.
    InterProiIPR014033. Arginase.
    IPR006035. Ureohydrolase.
    IPR023696. Ureohydrolase_domain.
    IPR020855. Ureohydrolase_Mn_BS.
    [Graphical view]
    PANTHERiPTHR11358. PTHR11358. 1 hit.
    PfamiPF00491. Arginase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF036979. Arginase. 1 hit.
    PRINTSiPR00116. ARGINASE.
    TIGRFAMsiTIGR01229. rocF_arginase. 1 hit.
    PROSITEiPS01053. ARGINASE_1. 1 hit.
    PS51409. ARGINASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6CLS8-1 [UniParc]FASTAAdd to Basket

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    MSSDPRFDFF QQKKLGIVLA PFSGGQPKSG VENGPKYLMK QGLRSDIESL    50
    GWETTLEEPL KGRDFESGKN DETDVYGIMK RPNLVGEATK LIYESVKKVS 100
    NEGRLAVTLG GDHSIAIGTV AGVLDKYPNA GLLWIDAHAD INTCSTTESG 150
    NIHGCPVSFL MGLDAKNTPP SLKWVPKCLD PKKIAYIGLR DVDAAERKIL 200
    KDNGIASYSM YHVDRYGLNK VIEMALEKVA PNGDEPIMVS YDVDAIDPLY 250
    VPATGTPVRG GLTLREGLFL VERIAETGRL VALDVVECNP ELASHDGHVV 300
    DTITTGCSIA RCALGETLL 319
    Length:319
    Mass (Da):34,535
    Last modified:August 16, 2004 - v1
    Checksum:i021AEE6C115B656E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR382126 Genomic DNA. Translation: CAG97818.1.
    RefSeqiXP_455111.1. XM_455111.1.

    Genome annotation databases

    GeneIDi2895828.
    KEGGikla:KLLA0F00704g.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR382126 Genomic DNA. Translation: CAG97818.1 .
    RefSeqi XP_455111.1. XM_455111.1.

    3D structure databases

    ProteinModelPortali Q6CLS8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 28985.Q6CLS8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2895828.
    KEGGi kla:KLLA0F00704g.

    Phylogenomic databases

    HOGENOMi HOG000204319.
    KOi K01476.
    OMAi KEQECDV.
    OrthoDBi EOG7X0VT2.

    Family and domain databases

    Gene3Di 3.40.800.10. 1 hit.
    InterProi IPR014033. Arginase.
    IPR006035. Ureohydrolase.
    IPR023696. Ureohydrolase_domain.
    IPR020855. Ureohydrolase_Mn_BS.
    [Graphical view ]
    PANTHERi PTHR11358. PTHR11358. 1 hit.
    Pfami PF00491. Arginase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF036979. Arginase. 1 hit.
    PRINTSi PR00116. ARGINASE.
    TIGRFAMsi TIGR01229. rocF_arginase. 1 hit.
    PROSITEi PS01053. ARGINASE_1. 1 hit.
    PS51409. ARGINASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome evolution in yeasts."
      Genolevures
      Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.
      , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.
      Nature 430:35-44(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37Imported.

    Entry informationi

    Entry nameiQ6CLS8_KLULA
    AccessioniPrimary (citable) accession number: Q6CLS8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 16, 2004
    Last sequence update: August 16, 2004
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3