Reviewed,
UniProtKB/Swiss-Prot Q6CKI0 (MCES_KLULA)
Last modified
June 16, 2009.
Version 34.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: mRNA cap guanine-N7 methyltransferase EC=2.1.1.56 Alternative name(s): mRNA (guanine-N(7)-)-methyltransferase mRNA cap methyltransferase | ||||
| Gene names |
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| Organism | Kluyveromyces lactis (Yeast) (Candida sphaerica) [Complete proteome] | ||||
| Taxonomic identifier | 28985 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Kluyveromyces |
Protein attributes
| Sequence length | 426 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Responsible for methylating the 5'-cap structure of mRNAs By similarity. |
| Catalytic activity | S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. |
| Subcellular location | Nucleus By similarity. |
| Sequence similarities | Belongs to the mRNA cap methyltransferase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | mRNA capping mRNA processing |
| Cellular component | Nucleus |
| Ligand | RNA-binding S-adenosyl-L-methionine |
| Molecular function | Methyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | mRNA capping Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | RNA binding Inferred from electronic annotation. Source: UniProtKB-KW mRNA (guanine-N7-)-methyltransferase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 426 | 426 | mRNA cap guanine-N7 methyltransferase | PRO_0000303909 | |||
Sequences
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References
| [1] | "Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. Souciet J.-L.Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NRRL Y-1140 / WM37. |
Cross-references
Sequence databases | |
|---|---|
| CR382126 Genomic DNA. Translation: CAG98267.1. | |
| RefSeq | XP_455559.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2895726. |
| KEGG | kla:KLLA0F10527g. |
Phylogenomic databases | |
| HOGENOM | Q6CKI0. |
| OMA | Q6CKI0. WLEDAID. |
Enzyme and pathway databases | |
| BRENDA | 2.1.1.56. 74088. |
Family and domain databases | |
| InterPro | IPR016899. mRNA_G-N7_MeTrfase. IPR004971. Pox_MCEL. [Graphical view] |
| Pfam | PF03291. Pox_MCEL. 1 hit. [Graphical view] |
| PIRSF | PIRSF028762. ABD1. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MCES_KLULA | ||||||||
| Accession | Primary (citable) accession number: Q6CKI0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||

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