Q6CKI0 (MCES_KLULA) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 49.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: mRNA cap guanine-N7 methyltransferase EC=2.1.1.56 Alternative name(s): mRNA (guanine-N(7)-)-methyltransferase mRNA cap methyltransferase | ||||
| Gene names |
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| Organism | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) [Complete proteome] | ||||
| Taxonomic identifier | 284590 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Kluyveromyces |
Protein attributes
| Sequence length | 426 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Responsible for methylating the 5'-cap structure of mRNAs By similarity. |
| Catalytic activity | S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. |
| Subcellular location | Nucleus By similarity. |
| Sequence similarities | Belongs to the methyltransferase superfamily. mRNA cap methyltransferase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | mRNA capping mRNA processing |
| Cellular component | Nucleus |
| Ligand | RNA-binding S-adenosyl-L-methionine |
| Molecular function | Methyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | mRNA capping Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | RNA binding Inferred from electronic annotation. Source: UniProtKB-KW mRNA (guanine-N7-)-methyltransferase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 426 | 426 | mRNA cap guanine-N7 methyltransferase | PRO_0000303909 | |||
Sequences
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References
| [1] | "Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. Souciet J.-L.Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CR382126 Genomic DNA. Translation: CAG98267.1. |
| RefSeq | XP_455559.1. XM_455559.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1RI5 based on UniProtKB Q8SR66. |
| ProteinModelPortal | Q6CKI0. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q6CKI0. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 2895726. |
| GenomeReviews | Gene locus KLLA0F10527g in contig CR382126_GR. |
| KEGG | kla:KLLA0F10527g. |
Phylogenomic databases | |
| eggNOG | fuNOG05085. |
| HOGENOM | HBG377892. |
| OMA | WLEDAID. |
| OrthoDB | EOG4CZFR2. |
Family and domain databases | |
| InterPro | IPR016899. mRNA_G-N7_MeTrfase. IPR004971. Pox_MCEL. [Graphical view] |
| KO | K00565. |
| Pfam | PF03291. Pox_MCEL. 1 hit. [Graphical view] |
| PIRSF | PIRSF028762. ABD1. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MCES_KLULA | ||||||||
| Accession | Primary (citable) accession number: Q6CKI0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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