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Protein

Transcription factor IWS1

Gene

IWS1

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).By similarity

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor IWS1
Gene namesi
Name:IWS1
Ordered Locus Names:YALI0A20724g
OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Taxonomic identifieri284591 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
Proteomesi
  • UP000001300 Componenti: Chromosome A

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000833651 – 414Transcription factor IWS1Add BLAST414

Structurei

3D structure databases

SMRiQ6CGB2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini228 – 305TFIIS N-terminalPROSITE-ProRule annotationAdd BLAST78

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi62 – 134Asp-richAdd BLAST73

Sequence similaritiesi

Belongs to the IWS1 family.Curated

Phylogenomic databases

HOGENOMiHOG000001004.
InParanoidiQ6CGB2.
KOiK17498.
OMAiRPILNKS.
OrthoDBiEOG092C3BAH.

Family and domain databases

InterProiView protein in InterPro
IPR017923. TFIIS_N.
PfamiView protein in Pfam
PF08711. Med26. 1 hit.
PROSITEiView protein in PROSITE
PS51319. TFIIS_N. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6CGB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDTEKPIKS EEPVDEGVDR VDEEENVEEP AEDVGEAAEE ASEAPEEAPA
60 70 80 90 100
EAATTTEAAP ADDDEDDSDL SDLDEDEIKN AAIEDDDDDY NKLSAHRRKV
110 120 130 140 150
QSSGKKTLKK RATKDSRAAD DDEDEIDHSH IDLDPSMARR REIEARIDAA
160 170 180 190 200
MKPASQRRKK LGEDDIEMMQ DERISNLREK MRNAAIADAE SNREGQPATH
210 220 230 240 250
KLQLLPEVKD VLQKHHLADS ILDNNLLEAV RIWLEPLPDA SLPSYSIQEE
260 270 280 290 300
LFDALVRLPI KSIHLRESGL GKVVTFYRKS KQPQLRIKRI ADKLVADWTR
310 320 330 340 350
PIMGRSDNYR EKVVSTRSFD PSTQEIALAV AAKRAQTLKD GTLAEKQAER
360 370 380 390 400
RRRAHIPSAQ PANYRVAPKS EIIPQNRGGS TNDMTFKRLK GKLGVTKTGK
410
KKSGVSIEGR GLNG
Length:414
Mass (Da):46,235
Last modified:August 16, 2004 - v1
Checksum:i1575721C65E7D43A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382127 Genomic DNA. Translation: CAG84238.1.
RefSeqiXP_500300.1. XM_500300.1.

Genome annotation databases

EnsemblFungiiCAG84238; CAG84238; YALI0_A20724g.
GeneIDi2905784.
KEGGiyli:YALI0A20724g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382127 Genomic DNA. Translation: CAG84238.1.
RefSeqiXP_500300.1. XM_500300.1.

3D structure databases

SMRiQ6CGB2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAG84238; CAG84238; YALI0_A20724g.
GeneIDi2905784.
KEGGiyli:YALI0A20724g.

Phylogenomic databases

HOGENOMiHOG000001004.
InParanoidiQ6CGB2.
KOiK17498.
OMAiRPILNKS.
OrthoDBiEOG092C3BAH.

Family and domain databases

InterProiView protein in InterPro
IPR017923. TFIIS_N.
PfamiView protein in Pfam
PF08711. Med26. 1 hit.
PROSITEiView protein in PROSITE
PS51319. TFIIS_N. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiIWS1_YARLI
AccessioniPrimary (citable) accession number: Q6CGB2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: August 16, 2004
Last modified: May 10, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.