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Protein

Transcription factor IWS1

Gene

IWS1

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).By similarity

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor IWS1
Gene namesi
Name:IWS1
Ordered Locus Names:YALI0A20724g
OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Taxonomic identifieri284591 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
Proteomesi
  • UP000001300 Componenti: Chromosome A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000833651 – 414Transcription factor IWS1Add BLAST414

Interactioni

Protein-protein interaction databases

STRINGi4952.XP_500300.1

Structurei

3D structure databases

SMRiQ6CGB2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini228 – 305TFIIS N-terminalPROSITE-ProRule annotationAdd BLAST78

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi62 – 134Asp-richAdd BLAST73

Sequence similaritiesi

Belongs to the IWS1 family.Curated

Phylogenomic databases

HOGENOMiHOG000001004
InParanoidiQ6CGB2
KOiK17498
OMAiQMIKAAN
OrthoDBiEOG092C3BAH

Family and domain databases

Gene3Di1.20.930.10, 1 hit
InterProiView protein in InterPro
IPR035441 TFIIS/LEDGF_dom_sf
IPR017923 TFIIS_N
PfamiView protein in Pfam
PF08711 Med26, 1 hit
PROSITEiView protein in PROSITE
PS51319 TFIIS_N, 1 hit

Sequencei

Sequence statusi: Complete.

Q6CGB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDTEKPIKS EEPVDEGVDR VDEEENVEEP AEDVGEAAEE ASEAPEEAPA
60 70 80 90 100
EAATTTEAAP ADDDEDDSDL SDLDEDEIKN AAIEDDDDDY NKLSAHRRKV
110 120 130 140 150
QSSGKKTLKK RATKDSRAAD DDEDEIDHSH IDLDPSMARR REIEARIDAA
160 170 180 190 200
MKPASQRRKK LGEDDIEMMQ DERISNLREK MRNAAIADAE SNREGQPATH
210 220 230 240 250
KLQLLPEVKD VLQKHHLADS ILDNNLLEAV RIWLEPLPDA SLPSYSIQEE
260 270 280 290 300
LFDALVRLPI KSIHLRESGL GKVVTFYRKS KQPQLRIKRI ADKLVADWTR
310 320 330 340 350
PIMGRSDNYR EKVVSTRSFD PSTQEIALAV AAKRAQTLKD GTLAEKQAER
360 370 380 390 400
RRRAHIPSAQ PANYRVAPKS EIIPQNRGGS TNDMTFKRLK GKLGVTKTGK
410
KKSGVSIEGR GLNG
Length:414
Mass (Da):46,235
Last modified:August 16, 2004 - v1
Checksum:i1575721C65E7D43A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382127 Genomic DNA Translation: CAG84238.1
RefSeqiXP_500300.1, XM_500300.1

Genome annotation databases

EnsemblFungiiCAG84238; CAG84238; YALI0_A20724g
GeneIDi2905784
KEGGiyli:YALI0A20724g

Similar proteinsi

Entry informationi

Entry nameiIWS1_YARLI
AccessioniPrimary (citable) accession number: Q6CGB2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: August 16, 2004
Last modified: March 28, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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