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Q6CG88 (ALO_YARLI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-arabinono-1,4-lactone oxidase

Short name=ALO
EC=1.1.3.37
Alternative name(s):
L-galactono-gamma-lactone oxidase
Gene names
Name:ALO1
Ordered Locus Names:YALI0A21263g
OrganismYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) [Reference proteome]
Taxonomic identifier284591 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia

Protein attributes

Sequence length526 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2.

Cofactor

FAD By similarity.

Pathway

Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.

Subcellular location

Mitochondrion membrane By similarity. Note: Membrane-embedded By similarity.

Sequence similarities

Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

Contains 1 FAD-binding PCMH-type domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 526526D-arabinono-1,4-lactone oxidase
PRO_0000128170

Regions

Domain22 – 196175FAD-binding PCMH-type

Amino acid modifications

Modified residue591Pros-8alpha-FAD histidine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6CG88 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 19AC25D2944948A1

FASTA52658,900
        10         20         30         40         50         60 
MSLRNSTTAK RFHSHKTWAG TFWSRPSLYF QPASIEELQA IVTRARDLGK TIMVVGSAHS 

        70         80         90        100        110        120 
PSDLTMTSQW LVNLDKLSKA VSFKPHTSGL YTDVTVEAGI RIHQLNEVLK RKGLAMQNLG 

       130        140        150        160        170        180 
SISDQSVAGI ISTGTHGSSA YHGLVSQQIV SLTIMIASGE LLTCSPDENP TLFRAALLSL 

       190        200        210        220        230        240 
GKLGIIVYAT LRTVPAYTIH STQHVITFET LIREWDNLWT ASEYIRVWWF PYAERCILWR 

       250        260        270        280        290        300 
ASKSELPLSA PRPSWYGTWL GRLFYETLLW VSVRLWPSLT PSVERFIFSR QYGMEDTLGS 

       310        320        330        340        350        360 
GTGSEAVQGS VEGLNMDCLF SQFVNEWGMP LDNGPDVLRA LRAKIEAAAK DNIYYVHSPV 

       370        380        390        400        410        420 
EVRCSNMSVP DSGDRNVEPN TQEFSASRRG AITGNTLRPL LDINPRDRPY ASPHGHVTNS 

       430        440        450        460        470        480 
NLTLYINATM YRPFGVNSPV GKWYRDFEGI VAEAGGKPHW AKNFLGPETA ELKDNESEDG 

       490        500        510        520 
KMLGLKPIID EWYGDDLKQW KSLREKYDPT GVFLSGKVWM DRNGLL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382127 Genomic DNA. Translation: CAG84262.1.
RefSeqXP_500324.1. XM_500324.1.

3D structure databases

ProteinModelPortalQ6CG88.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4952.Q6CG88.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCAG84262; CAG84262; YALI0_A21263g.
GeneID2906352.
KEGGyli:YALI0A21263g.

Phylogenomic databases

eggNOGCOG0277.
HOGENOMHOG000204635.
KOK00107.
OMAMDCLFSQ.
OrthoDBEOG7JX3CZ.

Enzyme and pathway databases

UniPathwayUPA00771; UER00766.

Family and domain databases

Gene3D3.30.43.10. 1 hit.
3.30.465.10. 1 hit.
InterProIPR007173. ALO.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR016167. FAD-bd_2_sub1.
IPR010031. FAD_lactone_oxidase.
IPR023595. LGO_GLO.
IPR006094. Oxid_FAD_bind_N.
[Graphical view]
PfamPF04030. ALO. 1 hit.
PF01565. FAD_binding_4. 1 hit.
[Graphical view]
PIRSFPIRSF000136. LGO_GLO. 1 hit.
SUPFAMSSF56176. SSF56176. 1 hit.
TIGRFAMsTIGR01678. FAD_lactone_ox. 1 hit.
PROSITEPS51387. FAD_PCMH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALO_YARLI
AccessionPrimary (citable) accession number: Q6CG88
Entry history
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: August 16, 2004
Last modified: February 19, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways