Q6CG74 (Q6CG74_YARLI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Nicotinate phosphoribosyltransferase RuleBase RU003838
EC=2.4.2.11 RuleBase RU003838

Gene names

Ordered Locus Names:

YALI0B00220g

Organism

Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)

Taxonomic identifier

284591 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Dipodascaceae › Yarrowia

Protein attributes

Sequence length	414 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. RuleBase RU003838
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate ribonucleotide from nicotinate: step 1/1. RuleBase RU003838
Sequence similarities	Belongs to the NAPRTase family. RuleBase RU003838

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis RuleBase RU003838
Molecular function	Glycosyltransferase RuleBase RU003838 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: InterPro nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: EC nicotinate-nucleotide diphosphorylase (carboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6CG74 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: BEE43045E145990F	FASTA	414	46,016
	10 20 30 40 50 60 MSTITSLLDT DLYKLTMQAA VLQHFPAAQA TFLFKNRTPS KQLNDDAIEW LKSEIAALGE 70 80 90 100 110 120 LRFTEDEIVF LQKHVGFLPA EYFEYLKTCQ LDPAAQVKVT VNTEGHLEIE VNGPWKDTIL 130 140 150 160 170 180 YEIPLLALVS EAYFKFVDKD WSYDGQSELA ATKAQELIAQ GCAFSEFGTR RRRSLKTHDI 190 200 210 220 230 240 VIAGILEGLK SAQGNGIFTG TSNVYLAKKY NLKPIGTVAH EWMMGVAAAT GDYSTANLRA 250 260 270 280 290 300 MELWIQTVGD ANAGVALTDT FGTESFLLDF NKPLTDIYNG VRQDSGDPLE YTKLLGDHYK 310 320 330 340 350 360 QLGYEPMSKV IVYSDSLDVE KCGKYKAAAA ENGLKAAFGV GTFFTNDFKR LSDGQKSTPL 370 380 390 400 410 NIVIKIQQLN GQSCIKLSDN LSKNMGDPET VERVKRELGY VEKGDVIDES KRWN

References

[1]

"Genome evolution in yeasts." Genolevures Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CLIB 122 / E 150.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR382128 Genomic DNA. Translation: CAG82552.1.
RefSeq	XP_500338.1. XM_500338.1.
3D structure databases
ProteinModelPortal	Q6CG74.
SMR	Q6CG74. Positions 3-401.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6CG74.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2907065.
GenomeReviews	Gene locus YALI0B00220g in contig CR382128_GR.
KEGG	yli:YALI0B00220g.
Phylogenomic databases
eggNOG	fuNOG05269.
HOGENOM	HBG325503.
OMA	HQFPQTH.
OrthoDB	EOG479JGB.
Family and domain databases
HAMAP	MF_00570. NAPRTase. [Tree]
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. IPR002638. Quinolinate_PRibosylTrfase_C. [Graphical view]
KO	K00763.
PANTHER	PTHR11098:SF1. NAPRTase. 1 hit.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
SUPFAM	SSF51690. Q_phspho_trans. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q6CG74_YARLI

Accession

Primary (citable) accession number: Q6CG74

Entry history

Integrated into UniProtKB/TrEMBL:	August 16, 2004
Last sequence update:	August 16, 2004
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)