Q6CG57 (KAD1_YARLI) Reviewed, UniProtKB/Swiss-Prot
Last modified
November 16, 2011.
Version 63.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Adenylate kinase 1 Short name=AK 1 EC=2.7.4.3 Alternative name(s): ATP-AMP transphosphorylase 1 Adenylate kinase cytosolic and mitochondrial | ||||
| Gene names |
| ||||
| Organism | Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) | ||||
| Taxonomic identifier | 284591 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Dipodascaceae › Yarrowia |
Protein attributes
| Sequence length | 251 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. This small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Functions both in cytoplasm and mitochondrion intermembrane space By similarity. |
| Catalytic activity | ATP + AMP = 2 ADP. |
| Subunit structure | Monomer By similarity. |
| Subcellular location | Cytoplasm › cytosol By similarity. Mitochondrion intermembrane space By similarity. |
| Sequence similarities | Belongs to the adenylate kinase family. AK2 subfamily. |
| Sequence caution | The sequence CAG82569.1 differs from that shown. Reason: Erroneous initiation. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm Mitochondrion |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Cellular component | cytosol Inferred from electronic annotation. Source: UniProtKB-SubCell mitochondrial intermembrane spaceInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW adenylate kinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| [1] | "Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. Souciet J.-L.Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CLIB 122 / E 150. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CR382128 Genomic DNA. Translation: CAG82569.1. Different initiation. |
| RefSeq | XP_500355.1. XM_500355.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1AKY based on UniProtKB P07170. |
| ProteinModelPortal | Q6CG57. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q6CG57. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 2907367. |
| GenomeReviews | Gene locus YALI0B00704g in contig CR382128_GR. |
| KEGG | yli:YALI0B00704g. |
Phylogenomic databases | |
| eggNOG | fuNOG05172. |
| HOGENOM | HBG630208. |
| OrthoDB | EOG4X0R28. |
Family and domain databases | |
| InterPro | IPR006259. Adenyl_kin_sub. IPR000850. Adenylate_kin. IPR007862. Adenylate_kinase_lid-dom. [Graphical view] |
| KO | K00939. |
| PANTHER | PTHR23359. Adenylate_kin. 1 hit. |
| Pfam | PF00406. ADK. 1 hit. PF05191. ADK_lid. 1 hit. [Graphical view] |
| PRINTS | PR00094. ADENYLTKNASE. |
| TIGRFAMs | TIGR01351. Adk. 1 hit. |
| PROSITE | PS00113. ADENYLATE_KINASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | KAD1_YARLI | ||||||||
| Accession | Primary (citable) accession number: Q6CG57 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with