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Q6CG11

- RIFK_YARLI

UniProt

Q6CG11 - RIFK_YARLI

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Protein
Riboflavin kinase
Gene
FMN1, YALI0B01826g
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme By similarity.

Catalytic activityi

ATP + riboflavin = ADP + FMN.

Cofactori

Zinc or magnesium By similarity.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi47 – 471Magnesium or zinc By similarity
Active sitei129 – 1291Nucleophile By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. riboflavin kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. FMN biosynthetic process Source: UniProtKB-UniPathway
  2. riboflavin biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Flavoprotein, FMN, Magnesium, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00276; UER00406.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin kinase (EC:2.7.1.26)
Alternative name(s):
Flavin mononucleotide kinase 1
Gene namesi
Name:FMN1
Ordered Locus Names:YALI0B01826g
OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Taxonomic identifieri284591 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
ProteomesiUP000001300: Chromosome B

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 192192Riboflavin kinase
PRO_0000301850Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi4952.Q6CG11.

Structurei

3D structure databases

ProteinModelPortaliQ6CG11.

Family & Domainsi

Sequence similaritiesi

Belongs to the flavokinase family.

Phylogenomic databases

eggNOGiCOG0196.
HOGENOMiHOG000260803.
KOiK00861.
OMAiLGWNPFY.
OrthoDBiEOG7K3V05.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
InterProiIPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF01687. Flavokinase. 1 hit.
[Graphical view]
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 2 hits.

Sequencei

Sequence statusi: Complete.

Q6CG11-1 [UniParc]FASTAAdd to Basket

« Hide

MMISCTRTAI LPLRRRLMTA STAYPIKFAS SIIPGYGRGS ADLGIPTANI    50
PIDDVPVLDA LDTGIYYGLV QILKTDKPSE KKTSEFQKDR VVDFQYTNKL 100
NDQEINAVLP MVMSVGWNPF YKNDQKSAEI HIIHKFAHTF YGASIKVMVL 150
GYLRPEKNFT SLEALVDEIH NDIKVSEEKM EGTREKKDQF WQ 192
Length:192
Mass (Da):21,820
Last modified:August 16, 2004 - v1
Checksum:iFC62F8024FB22660
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR382128 Genomic DNA. Translation: CAG82619.1.
RefSeqiXP_500401.1. XM_500401.1.

Genome annotation databases

EnsemblFungiiCAG82619; CAG82619; YALI0_B01826g.
GeneIDi2907158.
KEGGiyli:YALI0B01826g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR382128 Genomic DNA. Translation: CAG82619.1 .
RefSeqi XP_500401.1. XM_500401.1.

3D structure databases

ProteinModelPortali Q6CG11.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 4952.Q6CG11.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CAG82619 ; CAG82619 ; YALI0_B01826g .
GeneIDi 2907158.
KEGGi yli:YALI0B01826g.

Phylogenomic databases

eggNOGi COG0196.
HOGENOMi HOG000260803.
KOi K00861.
OMAi LGWNPFY.
OrthoDBi EOG7K3V05.

Enzyme and pathway databases

UniPathwayi UPA00276 ; UER00406 .

Family and domain databases

Gene3Di 2.40.30.30. 1 hit.
InterProi IPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view ]
PANTHERi PTHR22749. PTHR22749. 1 hit.
Pfami PF01687. Flavokinase. 1 hit.
[Graphical view ]
SMARTi SM00904. Flavokinase. 1 hit.
[Graphical view ]
SUPFAMi SSF82114. SSF82114. 2 hits.
ProtoNeti Search...

Entry informationi

Entry nameiRIFK_YARLI
AccessioniPrimary (citable) accession number: Q6CG11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: August 16, 2004
Last modified: January 22, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3