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Protein

1,4-alpha-glucan-branching enzyme

Gene

GLC3

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei333NucleophileBy similarity1
Active sitei398Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processGlycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan-branching enzyme (EC:2.4.1.18)
Alternative name(s):
Glycogen-branching enzyme
Gene namesi
Name:GLC3
Ordered Locus Names:YALI0C06798g
OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Taxonomic identifieri284591 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
Proteomesi
  • UP000001300 Componenti: Chromosome C

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001887851 – 6911,4-alpha-glucan-branching enzymeAdd BLAST691

Interactioni

Protein-protein interaction databases

STRINGi4952.XP_501531.1.

Structurei

3D structure databases

ProteinModelPortaliQ6CCT1.
SMRiQ6CCT1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000175159.
InParanoidiQ6CCT1.
KOiK00700.
OMAiEVVHGKS.
OrthoDBiEOG092C0QFK.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR006048. A-amylase/branching_C.
IPR006407. GlgB.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
PfamiView protein in Pfam
PF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
PIRSFiPIRSF000463. GlgB. 1 hit.
SMARTiView protein in SMART
SM00642. Aamy. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6CCT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLQVCKDDP WLKPFEEELL RRQALVGQWK DHFAKEGGLA EFAASYKRYG
60 70 80 90 100
LHVNKDNSVT YREWAPGASE AVLTGDFNGW DRQQYHMTRD EYGLWSVTVP
110 120 130 140 150
PTSDGQVAIP HNSKVKLALK TSNGQWVDRL PAWSTYVVQD LSKSPIYEAV
160 170 180 190 200
FWNPPESEKY QWKNKSPPTP ANAQIYEAHV GISSSEPRVG TYKEFTKNIL
210 220 230 240 250
PRIHKLGYNV IQLMAIMEHA YYASFGYQVT SFYAISSRYG TPEDLKELID
260 270 280 290 300
TAHGMGITVL LDVVHSHACK NVDDGLNNFD GTDHQYFHGG AKGDHPQWDS
310 320 330 340 350
KLFDYGKYEV LRFLLSNLRF YIEEYHFDGF RFDGVTSMLY KHHGLGTGFS
360 370 380 390 400
GGYHEYFGDE HVDQQAVVYL MLAHELMREL QPLLRPGEDA GNFLSIAEDV
410 420 430 440 450
SGMPALCRPV SEGGVGFDYR LAMAIPDMWI KLVKETRDED WDMGNIVFTL
460 470 480 490 500
TNRRHREKTI AYAESHDQAL VGDKTLAFWL MDKEMYTSMS VLSDPNPIID
510 520 530 540 550
RGIALHKMIR LITHSLGGEG YLNFEGNEFG HPEWLDFPRE GNGSSFHYCR
560 570 580 590 600
RQWPVVDDKL LRYQHLNEFD AAMQHRGDHY GWLSADQAYV SLKNEDDKVV
610 620 630 640 650
VYERAGLVFV FNFHPNKSFT DYRIGVDQPG TYTLVLDSDS PEFGGFGRID
660 670 680 690
HEKTRCHTEP LEWNGRANCM HIYIPSRVAL VFAREDDPRR K
Length:691
Mass (Da):79,306
Last modified:August 16, 2004 - v1
Checksum:i24D19060CFAB35C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382129 Genomic DNA. Translation: CAG81834.1.
RefSeqiXP_501531.1. XM_501531.1.

Genome annotation databases

EnsemblFungiiCAG81834; CAG81834; YALI0_C06798g.
GeneIDi2909223.
KEGGiyli:YALI0C06798g.

Similar proteinsi

Entry informationi

Entry nameiGLGB_YARLI
AccessioniPrimary (citable) accession number: Q6CCT1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: August 16, 2004
Last modified: September 27, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families