Q6C7U1 (CCPR3_YARLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative heme-binding peroxidase
EC=1.11.1.-

Gene names

Ordered Locus Names:

YALI0D25366g

Organism

Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) [Reference proteome]

Taxonomic identifier

284591 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Dipodascaceae › Yarrowia › Yarrowia lipolytica

Protein attributes

Sequence length	297 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.
Cofactor	Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity.
Sequence similarities	Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.

Ontologies

Keywords
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	response to oxidative stress Inferred from electronic annotation. Source: InterPro
Molecular_function	heme binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 297	297	Putative heme-binding peroxidase		PRO_0000055591
Sites
	Active site	74	1	Proton acceptor By similarity
	Active site	214	1	Tryptophan radical intermediate By similarity
	Metal binding	198	1	Iron (heme axial ligand) By similarity
	Site	70	1	Transition state stabilizer By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6C7U1 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 4A2069E287DAB5AF	FASTA	297	33,712
	10 20 30 40 50 60 MNYPSVSEQK HRVFIIYSAY LRVQFRESAR LAVSVRNKNY NLVRADLHNI LPQKNTTVFK 70 80 90 100 110 120 DGTLAPLLIR LAWHSCATYD KYTRTGGSNG ATMRYHLEAS DEGNVGLEVA RLSLEPIKRK 130 140 150 160 170 180 HPWITYADLW ILAGVVSIEA CKGPSIKWRD GRVDYEDDLL VPPNGRLPLG GGDASHVRTI 190 200 210 220 230 240 FSRMGFNDQE TVALIGAHSL GRLHHHRSGF DGPWTSNPAK CDNEFYKLLL GNVWTLVDSP 250 260 270 280 290 TGRKQYVNST GQVMMPSDMS LIEDANFRFW VDQYAVSEEL WRDHFALAFE KLTELGR

References

[1]

"Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CLIB 122 / E 150.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR382130 Genomic DNA. Translation: CAG81475.1.
RefSeq	XP_503271.1. XM_503271.1.
3D structure databases
ProteinModelPortal	Q6C7U1.
ModBase	Search...
Protein family/group databases
PeroxiBase	2365. YlCcP03.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2910665.
KEGG	yli:YALI0D25366g.
Phylogenomic databases
eggNOG	COG0376.
HOGENOM	HOG000189824.
OMA	EDANFRF.
OrthoDB	EOG45HW63.
Family and domain databases
InterPro	IPR002207. Asc_peroxidase. IPR010255. Haem_peroxidase. IPR002016. Haem_peroxidase_pln/fun/bac. IPR019794. Peroxidases_AS. IPR019793. Peroxidases_heam-ligand_BS. [Graphical view]
Pfam	PF00141. peroxidase. 1 hit. [Graphical view]
PRINTS	PR00459. ASPEROXIDASE. PR00458. PEROXIDASE.
SUPFAM	SSF48113. Peroxidase_super. 1 hit.
PROSITE	PS00435. PEROXIDASE_1. 1 hit. PS00436. PEROXIDASE_2. 1 hit. PS50873. PEROXIDASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CCPR3_YARLI

Accession

Primary (citable) accession number: Q6C7U1

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	August 16, 2004
Last modified:	May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program