Reviewed,
UniProtKB/Swiss-Prot Q6C7U0 (ATG1_YARLI)
Last modified
January 19, 2010.
Version 43.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: Serine/threonine-protein kinase ATG1 EC=2.7.11.1 Alternative name(s): Autophagy-related protein 1 | ||||
| Gene names |
| ||||
| Organism | Yarrowia lipolytica (Candida lipolytica) [Complete proteome] | ||||
| Taxonomic identifier | 4952 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Dipodascaceae › Yarrowia |
Protein attributes
| Sequence length | 710 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Serine/threonine protein kinase probably involved in the cytoplasm to vacuole transport (Cvt) and in autophagy, where it may be required for the formation of autophagosomes By similarity. |
| Catalytic activity | ATP + a protein = ADP + a phosphoprotein. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. Contains 1 protein kinase domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Autophagy Protein transport Transport |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Serine/threonine-protein kinase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | autophagy Inferred from electronic annotation. Source: UniProtKB-KW protein amino acid phosphorylationInferred from electronic annotation. Source: InterPro protein transportInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activityInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 710 | 710 | Serine/threonine-protein kinase ATG1 | PRO_0000085654 | |||||
Regions | |||||||||
| Domain | 7 – 299 | 293 | Protein kinase | ||||||
| Nucleotide binding | 13 – 21 | 9 | ATP By similarity | ||||||
Sites | |||||||||
| Active site | 150 | 1 | Proton acceptor By similarity | ||||||
| Binding site | 36 | 1 | ATP By similarity | ||||||
Sequences
| ||||||||||||||||||
References
| [1] | "Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. Souciet J.-L.Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CLIB 122 / E 150. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CR382130 Genomic DNA. Translation: CAG81476.1. |
| RefSeq | XP_503272.1. |
3D structure databases | |
| SMR | Q6C7U0. Positions 5-303. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2910666. |
| GenomeReviews | Gene locus YALI0D25388g in contig CR382130_GR. |
| KEGG | yli:YALI0D25388g. |
Phylogenomic databases | |
| eggNOG | fuNOG05347. |
| HOGENOM | HBG324852. |
| OMA | KYNAKAD. |
| OrthoDB | EOG98D2C4. |
| PhylomeDB | Q6C7U0. |
Enzyme and pathway databases | |
| BRENDA | 2.7.11.1. 3602. |
Family and domain databases | |
| InterPro | IPR020636. Ca/CaM-dep_prot_kinase-like. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_prot_kinase-like_dom. IPR008271. Ser/Thr_prot_kinase_AS. IPR020656. Ser/Thr_prot_kinase_ATG1. IPR002290. Ser/Thr_prot_kinase_dom. [Graphical view] |
| PANTHER | PTHR22982. Ca/CaM-dep_prot_kinase-like. 1 hit. PTHR22982:SF39. Ser/Thr_prot_kinase_ATG1. 1 hit. |
| Pfam | PF00069. Pkinase. 1 hit. [Graphical view] |
| SMART | SM00220. S_TKc. 1 hit. [Graphical view] |
| PROSITE | PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ATG1_YARLI | ||||||||
| Accession | Primary (citable) accession number: Q6C7U0 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||

Clusters with


