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Protein

Aconitate hydratase, mitochondrial

Gene

YALI0_E14949g

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

[4Fe-4S] clusterUniRule annotationNote: Binds 1 [4Fe-4S] cluster per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation
LigandIron, Iron-sulfurUniRule annotation, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Aconitate hydratase, mitochondrialUniRule annotation (EC:4.2.1.-UniRule annotation)
Short name:
AconitaseUniRule annotation
Gene namesi
ORF Names:YALI0_E14949gImported
OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)Imported
Taxonomic identifieri284591 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
Proteomesi
  • UP000001300 Componenti: Chromosome E

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MitochondrionUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi4952.XP_503960.1

Structurei

3D structure databases

ProteinModelPortaliQ6C5V2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini65 – 505AconitaseInterPro annotationAdd BLAST441
Domaini586 – 713Aconitase_CInterPro annotationAdd BLAST128

Sequence similaritiesi

Belongs to the aconitase/IPM isomerase family.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Phylogenomic databases

HOGENOMiHOG000224293
InParanoidiQ6C5V2
KOiK17450
OMAiQPRFYGC
OrthoDBiEOG092C0DQS

Family and domain databases

Gene3Di3.20.19.10, 1 hit
3.30.499.10, 2 hits
3.40.1060.10, 1 hit
InterProiView protein in InterPro
IPR015931 Acnase/IPM_dHydase_lsu_aba_1/3
IPR001030 Acoase/IPM_deHydtase_lsu_aba
IPR015928 Aconitase/3IPM_dehydase_swvl
IPR018136 Aconitase_4Fe-4S_BS
IPR036008 Aconitase_4Fe-4S_dom
IPR015932 Aconitase_dom2
IPR006248 Aconitase_mito-like
IPR000573 AconitaseA/IPMdHydase_ssu_swvl
PfamiView protein in Pfam
PF00330 Aconitase, 1 hit
PF00694 Aconitase_C, 1 hit
PRINTSiPR00415 ACONITASE
SUPFAMiSSF53732 SSF53732, 1 hit
TIGRFAMsiTIGR01340 aconitase_mito, 1 hit
PROSITEiView protein in PROSITE
PS00450 ACONITASE_1, 1 hit
PS01244 ACONITASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6C5V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRSARFCQA RFSAIKARGL ATTANASGLS VPADFKTRTP PYAELINRLD
60 70 80 90 100
QVKKIINRND LTLAEKILYS HLHNPEETPS ITRGDTYLKL NPDRVAMQDA
110 120 130 140 150
SAQMALLQFM TCGLPSTAVP ASIHCDHLIV GRDGADDDLT RSIATNQEVF
160 170 180 190 200
DFLQQCAEKY GIQFWGPGSG IIHQIVLENF SVPGLMMLGT DSHTPNAGGL
210 220 230 240 250
GAIAIGVGGA DAVDALTGTP WELKAPKILG VKLTGKLSGW ASPKDVITHL
260 270 280 290 300
AGKLTVRGGT GNIIEYHGEG VDSLSCTGMA TICNMGAEVG ATTSTFPFTE
310 320 330 340 350
SMRRYLEATG RAPIAAAAAA ARDRGFLAAD EGAQYDEVVE VNLSELEPCI
360 370 380 390 400
NGPFTPDLAT PLSKYSTKVT SEKWPDTVSA GLIGSCTNSS YEDMTRVASL
410 420 430 440 450
VEQARDNGLE AKIPFFITPG SEQIRATIKK DGLTDVFESA GAVVLANACG
460 470 480 490 500
PCIGQWDRTD ETKPGEFNSI FTSFNRNFRA RNDGNPETMN FLTSPEIVTA
510 520 530 540 550
MIYSGDAHFN PMTDSITTKD GKEFKFQPPK GTELPEEFAK GRPEFYPEAA
560 570 580 590 600
PQPHPEVNVT VSPDSERLQL LEPFEPFNNQ ELKLSVLMKV EGKCTTDHIS
610 620 630 640 650
AAGAWLKYKG HLENISYNTL IGALNKETQK VNHTIDAADG SEQSIPDLMI
660 670 680 690 700
KWKEQGKPWI VVAEHNYGEG SAREHAALSP RFLGGQAILV KSFARIHETN
710 720 730 740 750
LKKQGMLPLT FENEADYDKI QACDTLETLD LLDMLEKGGD NGGFVQMRAT
760 770 780 790
KSDGSTYDFR ARHTMSADQV DFFKAGSAIN FIGAQKAANK
Length:790
Mass (Da):85,638
Last modified:August 16, 2004 - v1
Checksum:iC1E2F9687D3DDD0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382131 Genomic DNA Translation: CAG79553.1
RefSeqiXP_503960.1, XM_503960.1

Genome annotation databases

EnsemblFungiiCAG79553; CAG79553; YALI0_E14949g
GeneIDi2911538
KEGGiyli:YALI0E14949g

Similar proteinsi

Entry informationi

Entry nameiQ6C5V2_YARLI
AccessioniPrimary (citable) accession number: Q6C5V2
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: May 23, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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