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Protein

Putative tyrosine-protein phosphatase OCA1

Gene

OCA1

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Putative tyrosine-protein phosphatase required for protection against superoxide stress.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei186 – 1861Phosphocysteine intermediateBy similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
Gene namesi
Name:OCA1
Ordered Locus Names:YALI0E22880g
OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Taxonomic identifieri284591 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
ProteomesiUP000001300: Chromosome E

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 253253Putative tyrosine-protein phosphatase OCA1PRO_0000333396Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi4952.Q6C4X9.

Structurei

3D structure databases

ProteinModelPortaliQ6C4X9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2365.
HOGENOMiHOG000188365.
InParanoidiQ6C4X9.
KOiK18043.
OMAiNINWELA.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSiPR01911. PFDSPHPHTASE.
SUPFAMiSSF52799. SSF52799. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6C4X9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHRTSIVEEL ERHQQDQKAD QEPGSVSDAS NSALQESSDP RLSTTDNTNT
60 70 80 90 100
PEINVNDQQQ EQQVASGEDT DPPSPRMKTI VKPPPIKVVP PLNFGPVERN
110 120 130 140 150
LYRSGQPEPI SFPFLEKLRL RTILWLAVED PSDNFLAFAD DHEIVVHHLG
160 170 180 190 200
LVTEGTNPWD QLTESSIVAA LQIIMDRDSY PLLVCCGMGR HRTGTIVGCL
210 220 230 240 250
RRLQGWNLAS VSEEYRRYAG SRGGRALIEL HIEAFDTSRI IVYPESAPEW

CSS
Length:253
Mass (Da):28,326
Last modified:August 16, 2004 - v1
Checksum:i7E1BEB86A27B26BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382131 Genomic DNA. Translation: CAG79882.1.
RefSeqiXP_504283.1. XM_504283.1.

Genome annotation databases

EnsemblFungiiCAG79882; CAG79882; YALI0_E22880g.
GeneIDi2912916.
KEGGiyli:YALI0E22880g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382131 Genomic DNA. Translation: CAG79882.1.
RefSeqiXP_504283.1. XM_504283.1.

3D structure databases

ProteinModelPortaliQ6C4X9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4952.Q6C4X9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAG79882; CAG79882; YALI0_E22880g.
GeneIDi2912916.
KEGGiyli:YALI0E22880g.

Phylogenomic databases

eggNOGiCOG2365.
HOGENOMiHOG000188365.
InParanoidiQ6C4X9.
KOiK18043.
OMAiNINWELA.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSiPR01911. PFDSPHPHTASE.
SUPFAMiSSF52799. SSF52799. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiOCA1_YARLI
AccessioniPrimary (citable) accession number: Q6C4X9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 16, 2004
Last modified: January 7, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.