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Q6C3Z9 (ACH1_YARLI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acetyl-CoA hydrolase

EC=3.1.2.1
Alternative name(s):
Acetyl-CoA deacylase
Short name=Acetyl-CoA acylase
Gene names
Name:ACH1
Ordered Locus Names:YALI0E30965g
OrganismYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) [Reference proteome]
Taxonomic identifier284591 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia

Protein attributes

Sequence length524 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation By similarity.

Catalytic activity

Acetyl-CoA + H2O = CoA + acetate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the acetyl-CoA hydrolase/transferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionacetyl-CoA hydrolase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 524524Acetyl-CoA hydrolase
PRO_0000215523

Sequences

Sequence LengthMass (Da)Tools
Q6C3Z9 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: EBF47FC1AE51C647

FASTA52458,051
        10         20         30         40         50         60 
MSAVLKQRIR YKPYLDKIRT AAQCVDLFGA KPNQYIGWSG FTGVGAPKVV PDAVSKHVEE 

        70         80         90        100        110        120 
NNLQGHENWR YNLFVGASAG MEIESRWANN NMIARRSPHQ VGKPIAAAIN EGRTDFFDKH 

       130        140        150        160        170        180 
LSMWAQDLTY GFYTRDKKEN SLDIAVIEAT AITEDGHLIP GPAVGASPEI VHMADKIIIE 

       190        200        210        220        230        240 
LNTKTPSFEG LHDINMPVLP PFRQPYQITD VSQKMGTPYI PLDPSKVVAI VESEFADVVG 

       250        260        270        280        290        300 
ANSPADEGSK AIAANLIELF QQEVKAGRLP ENLLPLQSGI GNIANAVVEG LADASFKDLN 

       310        320        330        340        350        360 
VWTEVLQDSF LDFFESGNLN FATATSIRLT EDGFKRFFDN WDEFSKKLLL RSQVVSNNPE 

       370        380        390        400        410        420 
IIRRLGVIAM NTPVEVDIYA HANSTCVNGS KMLHGLGGSG DFLRNAKLSI MHTPSARPSK 

       430        440        450        460        470        480 
TDPLGISCIV PFATHIDQTE HDLDIVVTEQ GLADLRGLSP KERSREMINK CAHPSYRDQL 

       490        500        510        520 
LAYVEQAEFE CAKSRSLHEP HVLKNAFKMH TNLAENGTMR LDKW 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382131 Genomic DNA. Translation: CAG80217.1.
RefSeqXP_504613.1. XM_504613.1.

3D structure databases

ProteinModelPortalQ6C3Z9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4952.Q6C3Z9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCAG80217; CAG80217; YALI0_E30965g.
GeneID2911920.
KEGGyli:YALI0E30965g.

Phylogenomic databases

eggNOGCOG0427.
HOGENOMHOG000172597.
KOK01067.
OMAASAGMEI.
OrthoDBEOG7TQV8M.

Family and domain databases

InterProIPR026888. AcetylCoA_hyd_C.
IPR003702. ActCoA_hydro.
[Graphical view]
PfamPF13336. AcetylCoA_hyd_C. 1 hit.
PF02550. AcetylCoA_hydro. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACH1_YARLI
AccessionPrimary (citable) accession number: Q6C3Z9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: August 16, 2004
Last modified: June 11, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families